DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG13579 and Kiss1r

DIOPT Version :9

Sequence 1:NP_001261169.1 Gene:CG13579 / 37905 FlyBaseID:FBgn0035010 Length:716 Species:Drosophila melanogaster
Sequence 2:NP_076482.2 Gene:Kiss1r / 78976 RGDID:70930 Length:396 Species:Rattus norvegicus


Alignment Length:458 Identity:94/458 - (20%)
Similarity:140/458 - (30%) Gaps:171/458 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly    46 VLTLGVIGANCLVIFVINNRRYAAYIHQQ--PRYLLTSLALNDLTIGLLITPFGLMPALFHCWPY 108
            ::.||::| |.||||||...:     |.|  ..:.:.:||..|:|..|...||..:......|..
  Rat    52 LMLLGLVG-NSLVIFVICRHK-----HMQTVTNFYIANLAATDVTFLLCCVPFTALLYPLPTWVL 110

  Fly   109 GEIFCQIQALLRGALSQQSAVILVCMAVDRYMCALHPRRYYQHSSKKGCVAILSLTWI----ISL 169
            |:..|:....::....|.:...|..|:|||:...:.|.|.....:.:..:.:....|:    :|.
  Rat   111 GDFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALTVSLSIWVGSAAVSA 175

  Fly   170 TVFGFLVLPKGYYFNNTGLMACEPFYSKP---SYRILSTCALYFPTTMVLMYCYGSSF-HMSRFR 230
            .|.....|..|.:     ....|.|.|:.   ::.:.:..|||....:....|||:.. |:.|  
  Rat   176 PVLALHRLSPGPH-----TYCSEAFPSRALERAFALYNLLALYLLPLLATCACYGAMLRHLGR-- 233

  Fly   231 LNDPTMPLTAAAHHPHPHPHPTAAQQLQMHQHQQHHQQAGMHSHLYHGHSHHPSHPSHPNHPNHH 295
                      ||..|.|.......|.|.        |:||                         
  Rat   234 ----------AAVRPAPTDGALQGQLLA--------QRAG------------------------- 255

  Fly   296 GHPHHHGPPVMGHLSMAMSMGLAGMPNMTNKITKKIVPIQEKNSSGSTSRSMAAISLGFIVMVTP 360
                                          .:..|:            ||.:||:.|.|      
  Rat   256 ------------------------------AVRTKV------------SRLVAAVVLLF------ 272

  Fly   361 WTIQEIVTACTGSKLPPFLDFLV--------TW----------------TALSNSLWNPFMYWLL 401
                   .||.|    |...|||        .|                .:.|||..||.:|..|
  Rat   273 -------AACWG----PIQLFLVLQALGPSGAWHPRSYAAYALKIWAHCMSYSNSALNPLLYAFL 326

  Fly   402 NSDFRRMSRQLMPNKCFPHEDTPEHKSGCCHIN------------ANDFEITTLPIPPEP--PSS 452
            .|.||:...::.|  |.|......|.|  .|.:            |:...:.|    |||  |..
  Rat   327 GSHFRQAFCRVCP--CGPQRQRRPHAS--AHSDRAAPHSVPHSRAAHPVRVRT----PEPGNPVV 383

  Fly   453 RPP 455
            |.|
  Rat   384 RSP 386

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG13579NP_001261169.1 7tm_4 51..>148 CDD:304433 27/98 (28%)
Kiss1rNP_076482.2 7tmA_KiSS1R 43..334 CDD:320223 80/396 (20%)
TM helix 1 45..69 CDD:320223 10/17 (59%)
TM helix 2 78..100 CDD:320223 7/21 (33%)
TM helix 3 116..138 CDD:320223 3/21 (14%)
TM helix 4 161..177 CDD:320223 2/15 (13%)
TM helix 5 202..225 CDD:320223 4/22 (18%)
TM helix 6 262..284 CDD:320223 11/38 (29%)
TM helix 7 302..327 CDD:320223 6/24 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 346..396 11/47 (23%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24230
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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