Protein Alignment CG13579 and Gpr173

DIOPT Version :10

• Sequence 1: NP_001261169.1
• Gene: CG13579 / 37905
• FlyBaseID: FBgn0035010
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_081819.2
• Gene: Gpr173 / 70771
• MGIID: 1918021
• Length: 373
• Species: Mus musculus
• Alignment Length: 418
• Identity: 83/418 - (19%)
• Similarity: 148/418 - (35%)
• Gaps: 95/418 - (22%)

  Fly    39 IEAVLI-LVLTLGVIGANCLVIFVINNRRYAAYIHQQPRYLLTSLALNDLTIGLLITPFGLMPAL 102
            ::.||: |::.:.:.|...|.:.|:..|.    :|:.|.|.|..|.|.|.....:..|| ::.::
Mouse    24 VKLVLLGLIMCVSLAGNAILSLLVLKERA----LHKAPYYFLLDLCLADGIRSAICFPF-VLASV 83

  Fly   103 FH--CWPYGEIFCQIQALLRGALSQQSAVILVCMAVDRYMCALHPRRYYQHSSKKGCVAILSLTW 165
            .|  .|.:..:.|:|.|.:.......:|.:|.|::|.|||...|.|.|.:..:...|.|::.:.|
Mouse    84 RHGSSWTFSALSCKIVAFMAVLFCFHAAFMLFCISVTRYMAIAHHRFYAKRMTLWTCAAVICMAW 148

  Fly   166 IISLTVFGFLVLPKGYYFNNTGLMACEPFYSKPSYRIL---STCALYFPTTMVLMYCYGSSFHMS 227
            .:|:.                  ||..|.:...:|:.:   ..|.                |...
Mouse   149 TLSVA------------------MAFPPVFDVGTYKFIREEDQCI----------------FEHR 179

  Fly   228 RFRLNDP------TMPLTAAAHHPHPHPHPTAAQQLQMHQHQQHHQQAGMHSHLYHGHSHHPSHP 286
            .|:.||.      ...|.||.|                         |.....|...:.|....|
Mouse   180 YFKANDTLGFMLMLAVLMAATH-------------------------AVYGKLLLFEYRHRKMKP 219

  Fly   287 SHPNHPNHHGHPHHHGPPVMGHLSMAMSMG---------LAGMPNMTNKITKKIVPIQEKNSSGS 342
            .. ..|....:...|||...|..:.....|         |.|:....:..:::::.:.|......
Mouse   220 VQ-MVPAISQNWTFHGPGATGQAAANWIAGFGRGPMPPTLLGIRQNGHAASRRLLGMDEVKGEKQ 283

  Fly   343 TSRSMAAISLGFIVMVTPWTI----QEIVTACTGSKLPPFLDFLVTWTALSNSLWNPFMYWLLNS 403
            ..|...||:|.|:::.:|:.:    :..|.||.   :|........|.:.:.:..||.:.:|||.
Mouse   284 LGRMFYAITLLFLLLWSPYIVACYWRVFVKACA---VPHRYLATAVWMSFAQAAVNPIVCFLLNK 345

  Fly   404 DFRRMSRQLMPNKCFPHEDTPEHKSGCC 431
            |.::..|...|  |:.....|..:...|
Mouse   346 DLKKCLRTHAP--CWGTGGAPAPREPYC 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13579	NP_001261169.1	7tm_classA_rhodopsin-like	41..>220	CDD:410626	40/184 (22%)
		TM helix 1	41..65	CDD:410626	6/24 (25%)
		TM helix 2	75..101	CDD:410626	8/25 (32%)
		TM helix 3	113..143	CDD:410626	10/29 (34%)
		TM helix 4	156..175	CDD:410626	4/18 (22%)
		TM helix 5	200..220	CDD:410626	2/22 (9%)
		7tm_GPCRs	<334..407	CDD:475119	18/76 (24%)
		TM helix 6	340..366	CDD:410628	6/29 (21%)
		TM helix 7	377..402	CDD:410628	4/24 (17%)
Gpr173	NP_081819.2	7tm_GPCRs	23..351	CDD:475119	78/394 (20%)
		TM helix 1	25..49	CDD:410628	6/23 (26%)
		TM helix 2	58..80	CDD:410628	7/22 (32%)
		TM helix 3	97..119	CDD:410628	5/21 (24%)
		TM helix 4	142..158	CDD:410628	5/33 (15%)
		TM helix 5	184..207	CDD:410628	7/47 (15%)
		TM helix 6	285..307	CDD:410628	6/21 (29%)
		TM helix 7	319..344	CDD:410628	4/24 (17%)