Protein Alignment CG13579 and Cysltr2

DIOPT Version :10

• Sequence 1: NP_001261169.1
• Gene: CG13579 / 37905
• FlyBaseID: FBgn0035010
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_598481.2
• Gene: Cysltr2 / 70086
• MGIID: 1917336
• Length: 309
• Species: Mus musculus
• Alignment Length: 430
• Identity: 67/430 - (15%)
• Similarity: 122/430 - (28%)
• Gaps: 177/430 - (41%)

  Fly    24 YSGHNFIAHIGIAETIEAVLILVLTLGVIGANCLVIFVINNRRYAAYIHQQPRYLLT---SLALN 85
            ||..|........|....:.:::...|.:| |...|:|               :|.|   |.::|
Mouse    10 YSNRNCTIENFKKEFYPIIYLIIFFWGALG-NGFSIYV---------------FLQTCKKSTSVN 58

  Fly    86 DLTIGLLITPFGLMPAL-FHC--------WPYGEIFCQIQALLRGALSQQSAVILVCMAVDRYMC 141
            ...:.|..:.|..:..| |..        |.:|::.|::.:.........|...|..::|.|::.
Mouse    59 VFMLNLATSDFLFISTLPFRADYYFRGSNWIFGDLACRVMSYSLYVNMYTSIYFLTVLSVVRFLA 123

  Fly   142 ALHPRRYYQHSSKKGCVAILSLTWIISLTVFGFLVLPKGYYFNNTGLMACEPFYSKPSYRILSTC 206
            .:||.|.:..:|.:....:..:.|:. :.....|:|..|               .:....|:|..
Mouse   124 TVHPFRMFHVTSVRSAWILCGIIWVF-IMASSALLLVNG---------------QEEKDNIISCL 172

  Fly   207 ALYFPTTMVLMYCYGSSFHMSRFRLNDPTMPLTAAAHHPHPHPHPTAAQQLQMHQHQQHHQQAGM 271
            .|                                         .|...:.|.
Mouse   173 EL-----------------------------------------SPQKFKSLL------------- 183

  Fly   272 HSHLYHGHSHHPSHPSHPNHPNHHGHPHHHGPPVMGHLSMAMSMGLAGMPNMTNKITK----KIV 332
                                             :|.|:::|:...|   |.:|..:..    :|:
Mouse   184 ---------------------------------IMNHIAVAVGFLL---PFLTLTVCYLLIIRIL 212

  Fly   333 PIQEKNSSGSTSRSMAAISLGFIVMVTPWTIQEIVTACTGSKLPPFLDF-------LVTW----- 385
            ...|...||..:....|::...|.|:|       ...|       ||.:       ||||
Mouse   213 LKAEIPESGPRAAHRKALTTIVIAMIT-------FLLC-------FLPYHALRTLHLVTWDKDSC 263

  Fly   386 -------------TALSNSLWNPFMYWLLNSDFRRMSRQL 412
                         .|.:||.:|||:|:....:|:...|.:
Mouse   264 GDVLHKATVITLTMAAANSCFNPFLYYFAGENFKARLRAI 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13579	NP_001261169.1	7tm_classA_rhodopsin-like	41..>220	CDD:410626	31/190 (16%)
		TM helix 1	41..65	CDD:410626	5/23 (22%)
		TM helix 2	75..101	CDD:410626	6/28 (21%)
		TM helix 3	113..143	CDD:410626	5/29 (17%)
		TM helix 4	156..175	CDD:410626	1/18 (6%)
		TM helix 5	200..220	CDD:410626	3/19 (16%)
		7tm_GPCRs	<334..407	CDD:475119	22/97 (23%)
		TM helix 6	340..366	CDD:410628	6/25 (24%)
		TM helix 7	377..402	CDD:410628	13/49 (27%)
Cysltr2	NP_598481.2	7tm_GPCRs	23..300	CDD:475119	63/412 (15%)
		TM helix 1	25..49	CDD:410628	5/39 (13%)
		TM helix 2	58..79	CDD:410628	5/20 (25%)
		TM helix 3	96..118	CDD:410628	2/21 (10%)
		TM helix 4	141..157	CDD:410628	1/16 (6%)
		TM helix 5	183..206	CDD:410628	6/71 (8%)
		TM helix 6	230..252	CDD:410628	6/35 (17%)
		TM helix 7	268..293	CDD:410628	7/24 (29%)