Protein Alignment CG13579 and gpr173

DIOPT Version :10

• Sequence 1: NP_001261169.1
• Gene: CG13579 / 37905
• FlyBaseID: FBgn0035010
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_571573.1
• Gene: gpr173 / 57926
• ZFINID: ZDB-GENE-000710-1
• Length: 387
• Species: Danio rerio
• Alignment Length: 444
• Identity: 88/444 - (19%)
• Similarity: 160/444 - (36%)
• Gaps: 123/444 - (27%)

  Fly    35 IAETIEAVLI-LVLTLGVIGANCLVIFVINNRRYAAYIHQQPRYLLTSLALNDLTIGLLITPFGL 98
            ::..::.||: |::.:.::|...:.:.|:.:|.    :|:.|.|.|..|.|.|.....:..||.|
Zfish    34 VSTYVKLVLLGLIICISLVGNLVVSLLVLRDRA----LHKAPYYFLLDLCLADTIRSAVCFPFVL 94

  Fly    99 MPAL-FHCWPYGEIFCQIQALLRGALSQQSAVILVCMAVDRYMCALHPRRYYQHSSKKGCVAILS 162
            :... ...|.|..:.|::.|.:.......:|.:|.|::|.|||...|.|.|.:..:...|||::.
Zfish    95 VSIKNGSAWTYSVLSCKVVAFMAVLFCFHAAFMLFCISVTRYMAIAHHRFYSKRMTFWTCVAVVC 159

  Fly   163 LTWIISLTVFGFLVLPKGYYFNNTGLMACEPFYSKPSYRIL---STCALYFPTTMVLMYCYGSSF 224
            :.|.:|:.                  ||..|.:...:|:.:   ..|.                |
Zfish   160 MVWTLSVA------------------MAFPPVFDVGTYKFIREEDQCI----------------F 190

  Fly   225 HMSRFRLNDP------TMPLTAAAHHPHPHPHPTAAQQLQMHQHQQHHQQAGMHSHLYHGHSHHP 283
            ....|:.||.      ...|..|.|        ....:|.:.:::                 |..
Zfish   191 EHRYFKANDTLGFMLMLAVLILATH--------VVYMKLLLFEYK-----------------HRK 230

  Fly   284 SHPSHPNHPNHHGHPHHHGPPVMGHLSMAMSMGLAG-----MP--------NMTNKITKKIVPIQ 335
            ..|.. ..|....:...|||   |....|.:..:||     ||        |:.|: .::::.::
Zfish   231 MKPVQ-MVPAISQNWTFHGP---GATGQAAANWIAGFGRGPMPPTLLGIRQNLHNQ-NRRLLGME 290

  Fly   336 EKNSSGSTSRSMAAISLGFIVMVTPWTI----QEIVTACTGSKLPPFLDFLVTWTALSNSLWNPF 396
            |..:.....|....|:|.|:|:.:|:.:    :..|.|||   :|........|.:.:.:..||.
Zfish   291 EFKAEKQLGRMFYVITLFFLVLWSPYIVACYWRVFVKACT---IPHRYLSTTVWMSFAQAGVNPI 352

  Fly   397 MYWLLNSDFRR-MSRQLMPNKCFPHEDTPEHKSGCCHINANDFEITTLPIPPEP 449
            :.:.||.|.:: :...|.|               ||.        |...:|.||
Zfish   353 ICFFLNKDLKKGLLAHLPP---------------CCR--------TPPQLPREP 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13579	NP_001261169.1	7tm_classA_rhodopsin-like	41..>220	CDD:410626	40/183 (22%)
		TM helix 1	41..65	CDD:410626	5/24 (21%)
		TM helix 2	75..101	CDD:410626	9/25 (36%)
		TM helix 3	113..143	CDD:410626	9/29 (31%)
		TM helix 4	156..175	CDD:410626	5/18 (28%)
		TM helix 5	200..220	CDD:410626	2/22 (9%)
		7tm_GPCRs	<334..407	CDD:475119	18/76 (24%)
		TM helix 6	340..366	CDD:410628	6/29 (21%)
		TM helix 7	377..402	CDD:410628	3/24 (13%)
gpr173	NP_571573.1	7tmA_SREB3_GPR173	37..365	CDD:320345	80/398 (20%)
		TM helix 1	38..64	CDD:320345	5/25 (20%)
		TM helix 2	71..96	CDD:320345	9/24 (38%)
		TM helix 3	110..140	CDD:320345	9/29 (31%)
		TM helix 4	152..174	CDD:320345	8/39 (21%)
		TM helix 5	195..224	CDD:320345	7/36 (19%)
		TM helix 6	293..323	CDD:320345	6/29 (21%)
		TM helix 7	333..358	CDD:320345	3/24 (13%)