DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13579 and Octbeta3R

DIOPT Version :9

Sequence 1:	NP_001261169.1	Gene:	CG13579 / 37905	FlyBaseID:	FBgn0035010	Length:	716	Species:	Drosophila melanogaster
Sequence 2:	NP_001034048.2	Gene:	Octbeta3R / 3885573	FlyBaseID:	FBgn0250910	Length:	1256	Species:	Drosophila melanogaster

Alignment Length:	815	Identity:	151/815 - (18%)
Similarity:	249/815 - (30%)	Gaps:	279/815 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 LILVLTLGVIGANCLVIFVINNRRYAAYIHQQPRYLLTSLALNDLTIGLLITPFGLMPALF-HCW 106
            :||...||    |.|||..:...|....|   ..|.:.|||:.|:.:.|....|.....|. ..|
  Fly   149 IILAAVLG----NALVIISVQRNRKLRVI---TNYFVVSLAMADMLVALCAMTFNASVELSGGKW 206

  Fly   107 PYGEIFCQIQALLRGALSQQSAVILVCMAVDRYMCALHPRRYYQHSSKKGCVAILSLTWIISLTV 171
            .:|...|.:...|....|..|.:.|.|::||||...:.|..|..:.:.|....:|:..||:. .:
  Fly   207 MFGPFMCNVYNSLDVYFSTASILHLCCISVDRYYAIVRPLEYPLNMTHKTVCFMLANVWILP-AL 270

  Fly   172 FGFLVLPKGYYFNNTGL--MACEP----FYSKPSYRILSTCALYFPTTMVLMYCYG--------- 221
            ..|..:..|:|.....|  ::..|    |....:|.::|:...::...:|::..|.
  Fly   271 ISFTPIFLGWYTTEEHLREISLHPDQCSFVVNKAYALISSSVSFWIPGIVMLVMYWRIFKEAIRQ 335

  Fly   222 -------------SSFHM---------SRFRLNDPTMPLTAAAHHPH------------------ 246
                         :|.||         |....:|..:..|:|....|
  Fly   336 RKALSRTSSNILLNSVHMGHTQQPTSLSYLHPSDCDLNATSAREETHSALSNLEDMLQPATDEDD 400

  Fly   247 ----------PHPHP-------------------------TAAQQLQMHQHQQHHQQAG-----M 271
                      |.|.|                         :|...:.:.|.|..|.|..     .
  Fly   401 DRDECDELRVPSPPPRRLSRSSIDLRDLEQERYEKVTHTDSAPSMMALQQQQPSHNQLQPPAPVF 465

  Fly   272 HSHLYHGHSHHPS-----HPSHPNHP-----------NHHGHPHHHGPPVMGHLSMAMSMG---- 316
            :..::......||     ..||||.|           |....|......|.|.|:...|.|
  Fly   466 NPQIWTEGKMIPSKELDKEHSHPNGPQQQLSLTSGSGNSEPEPESTAYRVFGGLNSDESEGNDLY 530

  Fly   317 -----LAGMPNMTNKITKKIVP---IQEKNSSGSTSRSMAAISLGFIVMVTPWTIQEIVTACTGS 373
                 ||    ..||..|:::.   :..|..:|.|                      |::...|.
  Fly   531 DTHLPLA----EDNKELKRLIEDNYLYFKRQTGGT----------------------IISGPGGG 569

  Fly   374 KLPPFLDFLVTWTALSNSLWNPFMYWLLNSDFRRM--SRQLMPNKCFPHEDTPEHKSGCCHINAN 436
            |          :.|||            .:||.|:  .......|.|...|             :
  Fly   570 K----------YAALS------------ETDFIRLKAGAAACGRKAFASSD-------------S 599

  Fly   437 DF-----EITTLPIPPEPPSSRPPGGAGGGGGGPSSGGPSSGGGVASSIGGSVLGICGRSRTNSL 496
            :|     |...||..|.|...:                           |.::|.:..:::.:|.
  Fly   600 EFLRTISESRALPEQPVPGKEK---------------------------GFNILSLLSKTKRSST 637

  Fly   497 SRSASQYIRGTMGGGVHNHQATETFST--TRPDIEGLSEKYWGEILERTVSSGNLNAMQKHLPPH 559
            .....:..|         |||....|:  .|.....||..|.|      ...|....:::
  Fly   638 ECFTLEKKR---------HQANSEGSSFFRRSRNRKLSHSYNG------CGGGKERKLER----- 682

  Fly   560 LPYAHHLVHQIHQPQQHHQQQTTSFSKASDLQLNLN-LSQAATAAELGKFSN-------SEPKL- 615
                          :|.....|.|.....|:.|::| ||:.:.|:.:.:||:       ||.|.
  Fly   683 --------------RQRQHSDTDSTPNKPDILLDINVLSEQSGASVIQQFSDGVQLIDFSELKTP 733

  Fly   616 CEHLFHDVNCAKSKAANGDGESSGKLAC---GRSIPDIXYAEDVILAKNQLLARQAKCSHHPLHQ 677
            .|.:..|...|  :.|:..|||..:.|.   ..|.|:: ....:::|.:..||...:....||.:
  Fly   734 PERIRSDDELA--QLADCFGESPQQPATPPPSLSPPELPEPSGLLIASSSELAEIFRSLSFPLGR 796

  Fly   678 Q--AKTRLHSHTGSLRFSRIRAACHSPPPEKSAFP 710
            .  |..||.:.:..:..:.:.:..::|.|...:.|
  Fly   797 PAGAPQRLSTLSDQVCANYLMSPPNTPAPPAISVP 831

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13579	NP_001261169.1	7tm_4	51..>148	CDD:304433	27/97 (28%)
Octbeta3R	NP_001034048.2	7tm_4	146..>346	CDD:304433	46/204 (23%)
Octbeta3R	NP_001034048.2	7tm_1	156..>344	CDD:278431	43/195 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460661
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930