DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG13579 and Dop2R

DIOPT Version :9

Sequence 1:NP_001261169.1 Gene:CG13579 / 37905 FlyBaseID:FBgn0035010 Length:716 Species:Drosophila melanogaster
Sequence 2:NP_001014758.2 Gene:Dop2R / 33007 FlyBaseID:FBgn0053517 Length:905 Species:Drosophila melanogaster


Alignment Length:560 Identity:117/560 - (20%)
Similarity:178/560 - (31%) Gaps:187/560 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    18 SCSHPRYSGHNFIAHIGIAETIEAVLILVLTLGVIGANCLVIFVINNRRYAAYIHQQPRYLLTSL 82
            ||...|...||:.|         .:|||...|.:.| |.|||..:...|   .:.....|.:.||
  Fly   366 SCGELRVVDHNYWA---------LILILFPILTLFG-NILVILSVCRER---SLQTVTNYFIVSL 417

  Fly    83 ALNDLTIGLLITPFGLMPALFHCWPYGEIFCQIQALLRGALSQQSAVILVCMAVDRYMCALHPRR 147
            |:.||.:.:::.||.:...:...|...::.|.....:....|..|...||.:::|||:....|.:
  Fly   418 AIADLLVAVVVMPFAVYFLVNGAWALPDVVCDFYIAMDVICSTSSIFNLVAISIDRYIAVTQPIK 482

  Fly   148 YYQH-SSKKGCVAILSLTWIISLTVFGFLVLPKGYYFNNTGLMACEP----FYSKPSYRILSTCA 207
            |.:| :|::.|:.|| |.|.||..:...:||.    .|||...  ||    ||:.......|..:
  Fly   483 YAKHKNSRRVCLTIL-LVWAISAAIGSPIVLG----LNNTPNR--EPDVCAFYNADFILYSSLSS 540

  Fly   208 LYFP-TTMVLMY-------------------------------------------CYGSSFHMSR 228
            .|.| ..||.:|                                           ...||.|.||
  Fly   541 FYIPCIIMVFLYWNIFKALRSRARKQRAARKPHLSELTGGSVIENIAQTRRLAETALDSSRHASR 605

  Fly   229 FRLNDPTMPLTAAAHHPHPHPHP------------------------------------TAAQQL 257
            . |.|.....||:..:.....:.                                    |...||
  Fly   606 I-LPDEAATNTASGSNEEEDENAISPDIDDCHVIVNDKSTEFMLATVVEETGNSVVAQITTQPQL 669

  Fly   258 QMHQHQQHHQQ-----------AGM--------------------HSHLYHGHSHHPSHPSHPNH 291
            .:.....:|..           ||:                    .|.|..|.:...|..|....
  Fly   670 VVADPNGNHDSGYAASNVDDVLAGVAPASASAATSAAPRSSGSPPDSPLPSGATLQRSSVSSQRR 734

  Fly   292 PNHHGHPHHHGPPV----MGHLSMAM------------SMGLAGMPNMTNKITKKIVPIQEKNSS 340
            |.....|....|.:    :.:.|:||            :|.||...:..:..:|......:|||.
  Fly   735 PTGDDSPKRGEPALRSVGVDNSSVAMKPLSFVRYGVQEAMTLARNDSTLSTTSKTSSRKDKKNSQ 799

  Fly   341 GS--------------TSRSMA----------AISLG-FIVMVTPWTIQEIVTA-CTGSK----- 374
            .|              ..:|.|          ||.|| |:....|:....|:.| |...|     
  Fly   800 ASRFTIYKVHKASKKKREKSSAKKERKATKTLAIVLGVFLFCWLPFFSCNIMDAMCAKFKKDCRP 864

  Fly   375 -LPPFLDFLVTWTALSNSLWNPFMYWLLNSDFRRMSRQLM 413
             |..::  :.||....||..||.:|.:.|.:||:..:::|
  Fly   865 GLTAYM--MTTWLGYINSFVNPVIYTIFNPEFRKAFKKIM 902

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG13579NP_001261169.1 7tm_4 51..>148 CDD:304433 24/96 (25%)
Dop2RNP_001014758.2 7tmA_D2-like_dopamine_R 376..>565 CDD:320181 55/208 (26%)
TM helix 1 377..403 CDD:320181 10/35 (29%)
TM helix 2 410..436 CDD:320181 8/25 (32%)
TM helix 3 448..478 CDD:320181 8/29 (28%)
TM helix 4 490..513 CDD:320181 8/23 (35%)
TM helix 5 529..558 CDD:320181 6/28 (21%)
7tm_GPCRs <822..898 CDD:333717 21/77 (27%)
TM helix 6 825..850 CDD:320095 6/24 (25%)
TM helix 7 866..891 CDD:320095 8/26 (31%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45460656
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.840

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