Protein Alignment CG13579 and TAAR6

DIOPT Version :10

• Sequence 1: NP_001261169.1
• Gene: CG13579 / 37905
• FlyBaseID: FBgn0035010
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_778237.1
• Gene: TAAR6 / 319100
• HGNCID: 20978
• Length: 345
• Species: Homo sapiens
• Alignment Length: 448
• Identity: 91/448 - (20%)
• Similarity: 145/448 - (32%)
• Gaps: 159/448 - (35%)

  Fly     7 SLLVAP----AVKNSSCSHPRYSGHNFIAHIGIAETIEAVLILVLTLGVIGA---NCLVIFVINN 64
            |||||.    |..|.||           ..|..:.....:|.:|...|.:.|   |.||:..|
Human     6 SLLVAVQLCYANVNGSC-----------VKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISI-- 57

  Fly    65 RRYAAYIHQQPRYLLTSLALNDLTIGLLITPFGLMPALFHCWPYGEIFCQIQALLRGALSQQSAV 129
             .:...:|....:|:.|||..|..:|:.:.||.::..:..||.:|..||........|....|..
Human    58 -LHFKQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLF 121

  Fly   130 ILVCMAVDRYMCALHPRRYYQHSSKKGCVAI----LSLTWIISLTVFGFLVLPKGYY-------- 182
            .|..:::|||:....|..|    ..|..|::    :|::||:.|...| .|...|.|
Human   122 HLCFISIDRYIAVTDPLVY----PTKFTVSVSGICISVSWILPLMYSG-AVFYTGVYDDGLEELS 181

  Fly   183 --FNNTGLMACEPFYSKPSYRILSTCALYFPTTMVLMYCYGSSFHMSRFRLNDPTMPLTAAAHHP 245
              .|..|  .|:...::  ..:|:....:|..|.:::..||:.|.::|
Human   182 DALNCIG--GCQTVVNQ--NWVLTDFLSFFIPTFIMIILYGNIFLVAR----------------- 225

  Fly   246 HPHPHPTAAQQLQMHQHQQHHQQAGMHSHLYHGHSHHPSHPSHPNHPNHHGHPHHHGPPVMGHLS 310
                                 :||
Human   226 ---------------------RQA----------------------------------------- 228

  Fly   311 MAMSMGLAGMPNMTNKITKKIVPIQEKNSSGSTS--------RSMAAISLG-----FIVMVTPWT 362
                              |||.....|..|.|.|        ...||.:||     |::...|::
Human   229 ------------------KKIENTGSKTESSSESYKARVARRERKAAKTLGVTVVAFMISWLPYS 275

  Fly   363 IQEIVTACTGSKLPPFLDFLVTWTALSNSLWNPFMYWLLNSDFRR-----MSRQLMPN 415
            |..::.|..|...|..:..:..|.|..||..||.:|.|....||:     ::.|::.|
Human   276 IDSLIDAFMGFITPACIYEICCWCAYYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKN 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13579	NP_001261169.1	7tm_classA_rhodopsin-like	41..>220	CDD:410626	46/195 (24%)
		TM helix 1	41..65	CDD:410626	8/26 (31%)
		TM helix 2	75..101	CDD:410626	8/25 (32%)
		TM helix 3	113..143	CDD:410626	7/29 (24%)
		TM helix 4	156..175	CDD:410626	6/22 (27%)
		TM helix 5	200..220	CDD:410626	3/19 (16%)
		7tm_GPCRs	<334..407	CDD:475119	23/85 (27%)
		TM helix 6	340..366	CDD:410628	10/38 (26%)
		TM helix 7	377..402	CDD:410628	8/24 (33%)
TAAR6	NP_778237.1	7tmA_TAAR6_8_9	33..322	CDD:320439	79/397 (20%)
		TM helix 1	34..60	CDD:320439	8/28 (29%)
		TM helix 2	67..93	CDD:320439	8/25 (32%)
		TM helix 3	105..135	CDD:320439	7/29 (24%)
		TM helix 4	147..170	CDD:320439	6/23 (26%)
		TM helix 5	194..223	CDD:320439	6/30 (20%)
		TM helix 6	251..281	CDD:320439	7/29 (24%)
		TM helix 7	290..315	CDD:320439	8/24 (33%)