Protein Alignment CG13579 and TAAR9

DIOPT Version :10

• Sequence 1: NP_001261169.1
• Gene: CG13579 / 37905
• FlyBaseID: FBgn0035010
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_778227.3
• Gene: TAAR9 / 134860
• HGNCID: 20977
• Length: 348
• Species: Homo sapiens
• Alignment Length: 412
• Identity: 79/412 - (19%)
• Similarity: 140/412 - (33%)
• Gaps: 112/412 - (27%)

  Fly    16 NSSCSHPRYSGHNFIAHIGIAETIEAVLILVLTLGVIGANCLVIFVINNRRYAAYIHQQPRYLLT 80
            |.||....||.       |....:.|||.....|...| |.||:..|   .:...:|....:|:.
Human    19 NESCIKTPYSP-------GPRSILYAVLGFGAVLAAFG-NLLVMIAI---LHFKQLHTPTNFLIA 72

  Fly    81 SLALNDLTIGLLITPFGLMPALFHCWPYGEIFCQIQALLRGALSQQSAVILVCMAVDRYMCALHP 145
            |||..|..:|:.:.||..:.::..||.:|:.:|:.......:....|...|.|::||||:....|
Human    73 SLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDP 137

  Fly   146 RRY---YQHSSKKGCVAILSLTWIISLTVFGFLVLPKGYYFNNTGL------MACEPFYSKPSYR 201
            ..|   :..|....|:.   |:|..|:| :.|.:...|  .|..|:      :.|......|..:
Human   138 LTYPTKFTVSVSGICIV---LSWFFSVT-YSFSIFYTG--ANEEGIEELVVALTCVGGCQAPLNQ 196

  Fly   202 --ILSTCALYFPTTMVLMYCYGSSFHMSRFRLNDPTMPLTAAAHHPHPHPHPTAAQQLQMHQHQQ 264
              :|....|:|...:.:::.|...|.:::
Human   197 NWVLLCFLLFFIPNVAMVFIYSKIFLVAK------------------------------------ 225

  Fly   265 HHQQAGMHSHLYHGHSHHPSHPSHPNHPNHHGHPHHHGPPVMGHLSMAMSMGLAGMPNMTNKITK 329
             ||...:.|......|...|:                                           |
Human   226 -HQARKIESTASQAQSSSESY-------------------------------------------K 246

  Fly   330 KIVPIQEKNSSGSTSRSMAAISLGFIVMVTPWTIQEIVTACTGSKLPPFLDFLVTWTALSNSLWN 394
            :.|..:|:.::.:...:|||    |:|...|:.:..::.|......||::..::.|....||..|
Human   247 ERVAKRERKAAKTLGIAMAA----FLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCVYYNSAMN 307

  Fly   395 PFMYWLLNSDFRRMSRQLMPNK 416
            |.:|......|.:..:.::..|
Human   308 PLIYAFFYQWFGKAIKLIVSGK 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13579	NP_001261169.1	7tm_classA_rhodopsin-like	41..>220	CDD:410626	46/189 (24%)
		TM helix 1	41..65	CDD:410626	9/23 (39%)
		TM helix 2	75..101	CDD:410626	8/25 (32%)
		TM helix 3	113..143	CDD:410626	8/29 (28%)
		TM helix 4	156..175	CDD:410626	5/18 (28%)
		TM helix 5	200..220	CDD:410626	3/21 (14%)
		7tm_GPCRs	<334..407	CDD:475119	17/72 (24%)
		TM helix 6	340..366	CDD:410628	6/25 (24%)
		TM helix 7	377..402	CDD:410628	7/24 (29%)
TAAR9	NP_778227.3	7tmA_TAAR6_8_9	33..322	CDD:320439	72/382 (19%)
		TM helix 1	34..60	CDD:320439	9/29 (31%)
		TM helix 2	67..93	CDD:320439	8/25 (32%)
		TM helix 3	105..135	CDD:320439	8/29 (28%)
		TM helix 4	147..170	CDD:320439	7/26 (27%)
		Extracellular Loop 2 (ECL2). /evidence=ECO:0000250|UniProtKB:Q5QD04	174..187		1/12 (8%)
		TM helix 5	194..223	CDD:320439	5/28 (18%)
		TM helix 6	251..281	CDD:320439	7/33 (21%)
		TM helix 7	290..315	CDD:320439	7/24 (29%)