DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG13579 and Kiss1r

DIOPT Version :9

Sequence 1:NP_001261169.1 Gene:CG13579 / 37905 FlyBaseID:FBgn0035010 Length:716 Species:Drosophila melanogaster
Sequence 2:NP_444474.1 Gene:Kiss1r / 114229 MGIID:2148793 Length:396 Species:Mus musculus


Alignment Length:468 Identity:95/468 - (20%)
Similarity:141/468 - (30%) Gaps:191/468 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly    46 VLTLGVIGANCLVIFVINNRRYAAYIHQQ--PRYLLTSLALNDLTIGLLITPFGLMPALFHCWPY 108
            ::.||::| |.|||:||...:     |.|  ..:.:.:||..|:|..|...||..:......|..
Mouse    52 LMLLGLVG-NSLVIYVICRHK-----HMQTVTNFYIANLAATDVTFLLCCVPFTALLYPLPAWVL 110

  Fly   109 GEIFCQIQALLRGALSQQSAVILVCMAVDRYMCALHPRRYYQHSSKKGCVAILSLTWIISLTVFG 173
            |:..|:....::....|.:...|..|:|||:...:.|.|.....:.:..:|:....|:.|..|..
Mouse   111 GDFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAVSLSIWVGSAAVSA 175

  Fly   174 -FLVL------PKGYYFNNTGLMACEPFYSKP---SYRILSTCALYFPTTMVLMYCYGSSF-HMS 227
             .|.|      |:.|        ..|.|.|:.   ::.:.:..|||....:....|||:.. |:.
Mouse   176 PVLALHRLSPGPRTY--------CSEAFPSRALERAFALYNLLALYLLPLLATCACYGAMLRHLG 232

  Fly   228 RFRLNDPTMPLTAAAHHPHPHPHPTAAQQLQMHQHQQHHQQAGMHSHLYHGHSHHPSHPSHPNHP 292
            |            ||..|.|.......|.|.        |:||                      
Mouse   233 R------------AAVRPAPTDGALQGQLLA--------QRAG---------------------- 255

  Fly   293 NHHGHPHHHGPPVMGHLSMAMSMGLAGMPNMTNKITKKIVPIQEKNSSGSTSRSMAAISLGFIVM 357
                                             .:..|:            ||.:||:.|.|   
Mouse   256 ---------------------------------AVRTKV------------SRLVAAVVLLF--- 272

  Fly   358 VTPWTIQEIVTACTGSKLPPFLDFLV--------TW----------------TALSNSLWNPFMY 398
                      .||.|    |...|||        .|                .:.|||..||.:|
Mouse   273 ----------AACWG----PIQLFLVLQALGPSGAWHPRSYAAYAVKIWAHCMSYSNSALNPLLY 323

  Fly   399 WLLNSDFRRMSRQLMPNKCFPHEDTPEHKSGCC-------HINANDFEITTLPIP---------- 446
            ..|.|.||:...::.|               ||       |.:|:.....|..:|          
Mouse   324 AFLGSHFRQAFCRVCP---------------CCRQRQRRPHTSAHSDRAATHTVPHSRAAHPVRI 373

  Fly   447 --PEP--PSSRPP 455
              |||  |..|.|
Mouse   374 RSPEPGNPVVRSP 386

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG13579NP_001261169.1 7tm_4 51..>148 CDD:304433 26/98 (27%)
Kiss1rNP_444474.1 7tmA_KiSS1R 43..334 CDD:320223 82/399 (21%)
TM helix 1 44..70 CDD:320223 9/18 (50%)
TM helix 2 77..103 CDD:320223 7/25 (28%)
TM helix 3 115..145 CDD:320223 7/29 (24%)
TM helix 4 157..177 CDD:320223 4/19 (21%)
TM helix 5 201..230 CDD:320223 6/28 (21%)
TM helix 6 256..286 CDD:320223 14/58 (24%)
TM helix 7 302..327 CDD:320223 6/24 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 349..396 10/38 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24230
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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