DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13579 and LOC110437881

DIOPT Version :9

Sequence 1:	NP_001261169.1	Gene:	CG13579 / 37905	FlyBaseID:	FBgn0035010	Length:	716	Species:	Drosophila melanogaster
Sequence 2:	XP_021328053.1	Gene:	LOC110437881 / 110437881	-ID:	-	Length:	332	Species:	Danio rerio

Alignment Length:	416	Identity:	92/416 - (22%)
Similarity:	143/416 - (34%)	Gaps:	127/416 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 NSSCSHPRYSGHNFIAHIGIAETIEAVLILVLTLGVIGANCLVIFVINNRRYAAYIHQQPRYLLT 80
            ||||...|:|...:|.        ..:.:.:|:...:..|.|||..|::.:   .:|.....::.
Zfish    18 NSSCVKGRHSSDGYIT--------TYLFVSLLSAWTVFLNLLVIISISHFK---KLHTPTNMIIL 71

  Fly    81 SLALNDLTIGLLITPFGLMPALFHCWPYGEIFCQIQALLRGALSQQSAVILVCMAVDRYMCALHP 145
            |||:.||.|| ||.|...:.....||.:|:.||.:..|....|...|...||.:||||||...||
Zfish    72 SLAVTDLFIG-LIMPIEAIRMTETCWYFGDTFCGLYFLFLALLLAASLGNLVLIAVDRYMAVCHP 135

  Fly   146 RRYYQHSSKKGCVAILSLTWIISLTVFGFLVLPKGY--YFNNTGLMACEPFYSKPSYRILSTCAL 208
            ..|.|..:....:..:.|:|:........:|:..||  :...|.|
Zfish   136 LLYPQKITTTKTLMCICLSWVCLSAYNTAIVISNGYFDFSRRTDL-------------------- 180

  Fly   209 YFPTTMVLMYCYGSSFHMSRFR--LNDPTM----PLTAAAHHPHPHPHPTAAQQLQMHQHQQHHQ 267
                      |||....|.||.  :.|..|    |.|...             .|.:......||
Zfish   181 ----------CYGQCLMMIRFSWIVTDLCMSCIFPCTLII-------------MLYLRIFFVVHQ 222

  Fly   268 QAGMHSHLYHGHSHHPSHPSHPNHPNHHGHPHHHGPPVMGHLSMAMSMGLAGMPNMTNKITKKIV 332
            |..:.:.|                                         :.|...:|....|:
Zfish   223 QVKVINSL-----------------------------------------ITGGKCVTEGSVKR-- 244

  Fly   333 PIQEKNSSGSTSRSMAAISLGFIVMV-----TPWTIQEIVTACTGSKLPPFLDFLVTWTALSNSL 392
                      .|.|.||::||.||.|     .|:.|      |:.:::|.....::.|...|||.
Zfish   245 ----------KSESKAALTLGIIVTVYMLCWIPYYI------CSLTEIPSTAMNVLIWAVHSNSG 293

  Fly   393 WNPFMYWLLNSDFRRMSRQLMPNKCF 418
            .||.:|.|....|::.::.::..:.|
Zfish   294 LNPLVYALFYRWFKKTAKLILMLEIF 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13579	NP_001261169.1	7tm_4	51..>148	CDD:304433	34/96 (35%)
LOC110437881	XP_021328053.1	7tmA_TAARs	32..309	CDD:320183	85/390 (22%)
		TM helix 1	33..59	CDD:320183	6/33 (18%)
		TM helix 2	66..91	CDD:320183	10/25 (40%)
		TM helix 3	103..133	CDD:320183	12/29 (41%)
		TM helix 4	145..168	CDD:320183	3/22 (14%)
		TM helix 5	190..219	CDD:320183	7/41 (17%)
		TM helix 6	245..275	CDD:320183	12/35 (34%)
		TM helix 7	278..303	CDD:320183	8/24 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D319105at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X43
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920