Protein Alignment CG13579 and kiss1r

DIOPT Version :10

• Sequence 1: NP_001261169.1
• Gene: CG13579 / 37905
• FlyBaseID: FBgn0035010
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_001163985.1
• Gene: kiss1r / 100316929
• XenbaseID: XB-GENE-990075
• Length: 366
• Species: Xenopus tropicalis
• Alignment Length: 423
• Identity: 77/423 - (18%)
• Similarity: 147/423 - (34%)
• Gaps: 127/423 - (30%)

  Fly    37 ETIEAVLI-----LVLTLGVIGANCLVIFVINNRRYAAYIHQQPR----YLLTSLALNDLTIGLL 92
            :.::|.|:     :::.:|:.| |.|||:||:.       |:|.|    :.:.:||..|:...:.
 Frog    38 QLVDAWLVPLFFAMLMLVGLTG-NSLVIYVISK-------HKQMRTVTNFYIANLAATDIIFLVS 94

  Fly    93 ITPFGLMPALFHC--WPYGEIFCQIQALLRGALSQQSAVILVCMAVDRYMCALHPRRYYQHSSKK 155
            ..||  ..||:..  |.:||..|:....::....|.:.|.|..|:|||:...::|.:..:..:.:
 Frog    95 CVPF--TAALYPLPGWIFGEFMCKFVNYIQQVSVQATCVTLTAMSVDRWYVTVYPLQSLRQRTPR 157

  Fly   156 GCVAILSLTW----IISLTVFGFLVLPKGYYFNNTGLMACEPFYS---KPSYRILSTCALYFPTT 213
            ...|:....|    |:|:.|..:..|.:||:| ...:...|.|.|   :.::.:.:...:|....
 Frog   158 VAAAVSVGIWIGSFIVSIPVPIYNQLIEGYWF-GPQIYCSESFPSVSHEKAFILYNFLVVYLLPL 221

  Fly   214 MVLMYCYGSSFHMSRFRLNDPTMPLTAAAHHPHPHPHPTAAQQLQMHQHQQHHQQAGMHSHLYHG 278
            :.:..||.
 Frog   222 ITICICYS--------------------------------------------------------- 229

  Fly   279 HSHHPSHPSHPNHPNHHGHPHHHGPPVMGHLSMAMSMGLAGMPNMTNKITKKIVPIQEKNSSGST 343
                                           :|...||...:..:.|....:::..:.:......
 Frog   230 -------------------------------AMVYQMGRPSVEPVDNSYQVQLLAERSELMRTKI 263

  Fly   344 SRSMAAISLGFIVMVTPWTIQEIVTACTGSKLPPFLDFLV-TWT---ALSNSLWNPFMYWLLNSD 404
            ||.:|.|.|.|.:...|..:..:..|.:.|....:..:.| .|.   :.:||..||.:|..:.::
 Frog   264 SRMVAVIVLLFTICWGPIQLYILFQAFSPSFKRDYYTYKVKIWANCMSYTNSSINPIVYAFMGAN 328

  Fly   405 FRRMSRQLMPNKCFPHEDTPE-HKSGCCHINAN 436
            ||:..     ||.||...... ..:|..:.|||
 Frog   329 FRKAF-----NKVFPFLFKQRVGSTGVANANAN 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13579	NP_001261169.1	7tm_classA_rhodopsin-like	41..>220	CDD:410626	45/196 (23%)
		TM helix 1	41..65	CDD:410626	10/28 (36%)
		TM helix 2	75..101	CDD:410626	6/29 (21%)
		TM helix 3	113..143	CDD:410626	8/29 (28%)
		TM helix 4	156..175	CDD:410626	5/22 (23%)
		TM helix 5	200..220	CDD:410626	1/19 (5%)
		7tm_GPCRs	<334..407	CDD:475119	17/76 (22%)
		TM helix 6	340..366	CDD:410628	7/25 (28%)
		TM helix 7	377..402	CDD:410628	7/28 (25%)
kiss1r	NP_001163985.1	7tmA_KiSS1R	43..333	CDD:320223	68/388 (18%)
		TM helix 1	44..70	CDD:320223	9/33 (27%)
		TM helix 2	77..103	CDD:320223	6/27 (22%)
		TM helix 3	115..145	CDD:320223	8/29 (28%)
		TM helix 4	157..177	CDD:320223	4/19 (21%)
		TM helix 5	205..234	CDD:320223	4/116 (3%)
		TM helix 6	258..288	CDD:320223	7/29 (24%)
		TM helix 7	301..326	CDD:320223	7/24 (29%)