DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13579 and gpr84

DIOPT Version :9

Sequence 1:	NP_001261169.1	Gene:	CG13579 / 37905	FlyBaseID:	FBgn0035010	Length:	716	Species:	Drosophila melanogaster
Sequence 2:	XP_021332416.1	Gene:	gpr84 / 100126017	ZFINID:	ZDB-GENE-070928-33	Length:	410	Species:	Danio rerio

Alignment Length:	441	Identity:	91/441 - (20%)
Similarity:	152/441 - (34%)	Gaps:	104/441 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 SCSHPRYSGHNFI-AHIGIAETIEAVLILVLTLGVIGANCLVI--FVINNRRYAAYIHQQPRYLL 79
            ||:.|...|:.:. ..:|.|.||         :|.|| |.|.:  ||.:     |.:..:...|:
Zfish    22 SCASPSVEGYRYFGVLLGSAVTI---------VGTIG-NILTVLAFVTD-----ANLRTRFNVLI 71

  Fly    80 TSLALNDLTIGLLITPFGLMPALFHCWPYGEIFCQIQALLRGALSQQSAVILVCM-AVDRYMCAL 143
            .:||..||....::.|..:...|...|..|..:|::..||. .||...::|.:|: |:.||:...
Zfish    72 VNLAFADLLYCTILQPVSVDSYLHLHWRGGATWCRMFGLLL-FLSNSVSIITLCLIAMSRYLVVA 135

  Fly   144 HPRRYYQH--SSKKGCVAILSLTWIISLTVFG-----FLVLP----------KG----------Y 181
            |.......  .|::|..|:|..:|::.|..|.     ::..|          ||          |
Zfish   136 HRTSSCARLLLSQRGVAALLISSWVLGLASFAPLWPVYVFAPQVCTCSFHRTKGRPYTTVLLFLY 200

  Fly   182 YFNNTGLMACEPFYSKPSYRILSTCALYFPTTMVLMYCYGSSFHMSRFRLND-----PTMPLTAA 241
            :|...|.:..  ||.. .||.:|..|..|       ..|..|...|:.:..:     ....::|.
Zfish   201 FFLGLGFVGL--FYFL-IYRKVSVAAKAF-------LKYRPSRRSSKRKQAEAEGTTDDSGISAG 255

  Fly   242 AHHPHPHPHPTAAQQLQMHQHQQHHQQAGMHSHLYHGHSHHPSHPSHPNHPNHHGHPHHHGPPVM 306
            |.........:.....:.|..|....|....:...|..|...|..|               |.|:
Zfish   256 ASTTQSCEISSDGAVAEQHGKQAQEGQTTTQNATQHASSETTSKAS---------------PVVI 305

  Fly   307 GHLSMAMSMGLAGMPNMTNKITKKIVPIQEKNSSGSTSRSMAAISLGFIVMVTPWTIQEIVTACT 371
            .:...|.:.|                   |.|.....:|....:.|.|:....|:.:..:  |..
Zfish   306 QNTPAAANSG-------------------EDNEFKRVTRMCFTVFLCFVGCFAPFLLLNV--ADK 349

  Fly   372 GSKLPPFLDFL---VTWTALSNSLWNPFMYWLLNSDFRRMSRQLMPNKCFP 419
            .::.|..:..:   :||.   ||..||.:|..:|..|.:..:.|:.....|
Zfish   350 KNRAPQVIHMICANLTWL---NSCINPLLYAAMNRQFNQAYKDLLSKAAHP 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13579	NP_001261169.1	7tm_4	51..>148	CDD:304433	27/99 (27%)
gpr84	XP_021332416.1	7tmA_GPR84-like	33..387	CDD:320338	85/418 (20%)
		TM helix 1	34..60	CDD:320338	11/35 (31%)
		TM helix 2	67..90	CDD:320338	6/22 (27%)
		TM helix 3	105..135	CDD:320338	10/30 (33%)
		TM helix 4	151..169	CDD:320338	5/17 (29%)
		TM helix 5	189..214	CDD:320338	6/26 (23%)
		TM helix 6	318..348	CDD:320338	5/31 (16%)
		TM helix 7	355..380	CDD:320338	7/27 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24230
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100