DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3494 and mfhas1

DIOPT Version :9

Sequence 1:	NP_611915.1	Gene:	CG3494 / 37903	FlyBaseID:	FBgn0035008	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	XP_001335202.2	Gene:	mfhas1 / 797005	ZFINID:	ZDB-GENE-080917-20	Length:	992	Species:	Danio rerio

Alignment Length:	232	Identity:	63/232 - (27%)
Similarity:	104/232 - (44%)	Gaps:	35/232 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 FPDKY-HMRNTRILQVSKAQISEVPMEVFEAAQQELVNIVSLD--GNRLLEMPKDLPLLSEHLTQ 89
            ||..: .:|..|.|.|...::...|.|:.     .|.::..||  ||:|..:|.::.:| :.:..
Zfish   155 FPRSFSQLRKLRTLDVDHNKLQRFPSEIL-----ALSDLEELDCSGNKLEGLPGNIMML-QSIKI 213

  Fly    90 LVLNKNQISFVPTNISQYSKLTNLSLSNNLLCDLPMELGGLRLLRNLDISHNRFRQLPRCIYELE 154
            |.|:...:..:|....:...|.:|.|.||.|..||...|.|:.|:.|::|.|.|...|:.|.:|.
Zfish   214 LWLSSTHLLSLPETFCELQNLESLMLDNNFLTRLPQSFGKLQKLKMLNLSSNSFEDFPQVIIKLT 278

  Fly   155 RLETLSAHDNQIRAIDASESGLGGMRELKRLNLGNNDIQIVPPI---LGKMQNLV---------- 206
            |||.|....|::..:...   :|.:..|..|.|.||.|..:|..   |||::.||
Zfish   279 RLEELYLSRNKLTFLPEE---VGQLCNLANLWLDNNSITFLPDSIVELGKLEELVLQGNQIAILP 340

  Fly   207 -------ELELW---GNPFRQPRHQILSMGTPALLSY 233
                   ::.:|   .||..||.:::...|.|.:.:|
Zfish   341 DNFGKLAKVNIWKVKDNPLIQPPYEVCMKGIPYIAAY 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3494	NP_611915.1	LRR	<34..>231	CDD:227223	60/221 (27%)
		leucine-rich repeat	38..62	CDD:275380	5/23 (22%)
		leucine-rich repeat	63..86	CDD:275380	7/24 (29%)
		LRR_4	85..124	CDD:289563	9/38 (24%)
		leucine-rich repeat	87..109	CDD:275380	3/21 (14%)
		leucine-rich repeat	110..133	CDD:275380	10/22 (45%)
		leucine-rich repeat	134..155	CDD:275380	7/20 (35%)
		leucine-rich repeat	156..181	CDD:275380	5/24 (21%)
		leucine-rich repeat	182..204	CDD:275380	10/24 (42%)
mfhas1	XP_001335202.2	LRR	25..>312	CDD:227223	47/165 (28%)
		leucine-rich repeat	31..48	CDD:275380
		leucine-rich repeat	49..72	CDD:275380
		leucine-rich repeat	73..95	CDD:275380
		leucine-rich repeat	96..118	CDD:275380
		leucine-rich repeat	119..141	CDD:275380
		leucine-rich repeat	142..164	CDD:275380	2/8 (25%)
		leucine-rich repeat	165..187	CDD:275380	6/26 (23%)
		leucine-rich repeat	188..233	CDD:275380	10/45 (22%)
		leucine-rich repeat	234..256	CDD:275380	10/21 (48%)
		leucine-rich repeat	257..279	CDD:275380	8/21 (38%)
		leucine-rich repeat	280..305	CDD:275380	6/27 (22%)
		leucine-rich repeat	306..325	CDD:275380	7/18 (39%)
		leucine-rich repeat	326..346	CDD:275380	2/19 (11%)
		P-loop_NTPase	391..>511	CDD:328724
		COR	630..858	CDD:318343
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000