DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3494 and LRRC40

DIOPT Version :9

Sequence 1:NP_611915.1 Gene:CG3494 / 37903 FlyBaseID:FBgn0035008 Length:240 Species:Drosophila melanogaster
Sequence 2:NP_060238.3 Gene:LRRC40 / 55631 HGNCID:26004 Length:602 Species:Homo sapiens


Alignment Length:202 Identity:81/202 - (40%)
Similarity:119/202 - (58%) Gaps:2/202 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly    38 RILQVSKAQISEVPMEVFEAAQQELVNIVSLDGNRLLEMPKDLPLLSEHLTQLVLNKNQISFVPT 102
            :||..|..|.:.:|.|||:|.:..:|..::...|:|.|:||.:..|.|.::.:.|:.|::||:..
Human   402 KILDYSDKQATLIPDEVFDAVKSNIVTSINFSKNQLCEIPKRMVELKEMVSDVDLSFNKLSFISL 466

  Fly   103 NISQYSKLTNLSLSNNLLCDLPMELGGLRLLRNLDISHNRFRQLPRCIYELERLETLSAHDNQIR 167
            .:....|||.|.|.||.|..||.|:..|..|:.:::|.|||:.||..:|.:..|||:...:||:.
Human   467 ELCVLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQVG 531

  Fly   168 AIDASESGLGGMRELKRLNLGNNDIQIVPPILGKMQNLVELELWGNPFRQPRHQILSMGTPALLS 232
            ::|..:..:  |..|..|:|.|||:..:||.||...||..|.|.|||||.||..||..||.|:|.
Human   532 SVDPQKMKM--MENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPFRVPRAAILMKGTAAILE 594

  Fly   233 YLRTRIP 239
            |||.|||
Human   595 YLRDRIP 601

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3494NP_611915.1 LRR <34..>231 CDD:227223 74/192 (39%)
leucine-rich repeat 38..62 CDD:275380 9/23 (39%)
leucine-rich repeat 63..86 CDD:275380 7/22 (32%)
LRR_4 85..124 CDD:289563 13/38 (34%)
leucine-rich repeat 87..109 CDD:275380 4/21 (19%)
leucine-rich repeat 110..133 CDD:275380 11/22 (50%)
leucine-rich repeat 134..155 CDD:275380 7/20 (35%)
leucine-rich repeat 156..181 CDD:275380 7/24 (29%)
leucine-rich repeat 182..204 CDD:275380 10/21 (48%)
LRRC40NP_060238.3 leucine-rich repeat 41..83 CDD:275380
LRR 1 83..104
LRR_8 84..140 CDD:316378
leucine-rich repeat 84..106 CDD:275380
LRR 2 106..127
leucine-rich repeat 107..129 CDD:275380
PLN00113 120..>577 CDD:331614 64/176 (36%)
LRR 3 129..150
leucine-rich repeat 130..152 CDD:275380
LRR 4 152..173
leucine-rich repeat 153..175 CDD:275380
LRR 5 175..196
leucine-rich repeat 176..198 CDD:275380
LRR 6 198..219
leucine-rich repeat 199..221 CDD:275380
LRR 7 221..242
leucine-rich repeat 222..244 CDD:275380
LRR 8 244..265
leucine-rich repeat 245..266 CDD:275380
LRR 9 266..286
leucine-rich repeat 267..290 CDD:275380
LRR 10 290..311
leucine-rich repeat 291..313 CDD:275380
LRR 11 313..335
LRR 12 336..356
LRR 13 400..421 8/18 (44%)
LRR 14 426..447 6/20 (30%)
leucine-rich repeat 447..473 CDD:275380 6/25 (24%)
LRR 15 450..472 4/21 (19%)
LRR 16 473..494 11/20 (55%)
leucine-rich repeat 474..496 CDD:275380 11/21 (52%)
LRR 17 496..517 8/20 (40%)
leucine-rich repeat 497..543 CDD:275380 15/47 (32%)
LRR 18 519..540 6/20 (30%)
LRR 19 543..564 10/20 (50%)
leucine-rich repeat 544..566 CDD:275380 10/21 (48%)
LRR 20 566..586 12/19 (63%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0472
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D295141at33208
OrthoFinder 1 1.000 - - FOG0005608
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.820

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