DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3494 and CG10307

DIOPT Version :9

Sequence 1:	NP_611915.1	Gene:	CG3494 / 37903	FlyBaseID:	FBgn0035008	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_001286690.1	Gene:	CG10307 / 37477	FlyBaseID:	FBgn0034655	Length:	341	Species:	Drosophila melanogaster

Alignment Length:	187	Identity:	56/187 - (29%)
Similarity:	91/187 - (48%)	Gaps:	9/187 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 LQVSKAQISEVPMEVFEAAQQELVNIVSLDGNRLLEMPKDLPLLSEHLTQLVLNKNQISFVPTNI 104
            |.:|..|||:|| .:.|..  |.:..:.|:.|:|.::|..:..|. .|..|.|:.|::...|..|
  Fly    28 LNLSHYQISDVP-GIIEKC--ETLMKLFLNQNKLTKIPSSIGSLM-RLQVLTLDYNKLDEFPLCI 88

  Fly   105 SQYSKLTNLSLSNNLLCDLPMELGGLRLLRNLDISHNRFRQLPRCIYELERLETLSAHDNQIRAI 169
            .:..:|..|::|.|.:..||.|||.|..|.....::....:||..|...|.||||....|.::.:
  Fly    89 CRLVRLKFLNISCNNISSLPPELGYLTQLETFWCNNTGLLELPNEIRNCEHLETLGVRGNPLKKL 153

  Fly   170 -DASESGLGGMRELKRLNLGNNDIQIVPPILGKMQNLVELELWGNPFRQPRHQILSM 225
             ||    :|.:..|:.|.....::..||..:..:.|||.|.|.||..|:....:::|
  Fly   154 PDA----IGALSSLRWLTAEGCELSEVPLTMALLGNLVHLNLKGNRLRRLPRMLMAM 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3494	NP_611915.1	LRR	<34..>231	CDD:227223	56/187 (30%)
		leucine-rich repeat	38..62	CDD:275380	8/21 (38%)
		leucine-rich repeat	63..86	CDD:275380	5/22 (23%)
		LRR_4	85..124	CDD:289563	10/38 (26%)
		leucine-rich repeat	87..109	CDD:275380	6/21 (29%)
		leucine-rich repeat	110..133	CDD:275380	10/22 (45%)
		leucine-rich repeat	134..155	CDD:275380	3/20 (15%)
		leucine-rich repeat	156..181	CDD:275380	8/25 (32%)
		leucine-rich repeat	182..204	CDD:275380	4/21 (19%)
CG10307	NP_001286690.1	leucine-rich repeat	27..44	CDD:275380	7/16 (44%)
		LRR_8	47..104	CDD:290566	15/57 (26%)
		leucine-rich repeat	48..70	CDD:275380	5/22 (23%)
		LRR	69..>244	CDD:227223	42/143 (29%)
		leucine-rich repeat	71..93	CDD:275380	6/21 (29%)
		leucine-rich repeat	94..116	CDD:275380	10/21 (48%)
		leucine-rich repeat	117..139	CDD:275380	4/21 (19%)
		leucine-rich repeat	140..162	CDD:275380	8/25 (32%)
		leucine-rich repeat	163..185	CDD:275380	4/21 (19%)
		leucine-rich repeat	186..208	CDD:275380	8/21 (38%)
		leucine-rich repeat	209..233	CDD:275380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467262
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45367
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.940