DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3494 and LRRC30

DIOPT Version :9

Sequence 1:NP_611915.1 Gene:CG3494 / 37903 FlyBaseID:FBgn0035008 Length:240 Species:Drosophila melanogaster
Sequence 2:NP_001099051.1 Gene:LRRC30 / 339291 HGNCID:30219 Length:301 Species:Homo sapiens


Alignment Length:228 Identity:68/228 - (29%)
Similarity:108/228 - (47%) Gaps:35/228 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    40 LQVSKAQISEVPMEVFEAAQQELVNIVSLDGNRLLEMPKDLPLLSEHLTQLVLNKNQISFVPTNI 104
            |.:|..|:..:|.||.:..:   :.:::|.||||..:|:::.|| :.|..|.:|.|.::.||..:
Human    76 LNLSHNQLRVLPPEVGKLTR---IVVLNLCGNRLKSLPREVSLL-QCLKVLFVNMNCLTEVPAEL 136

  Fly   105 SQYSKLTNLSLSNNLLCDLPMELGGLRLLRNLDISHNRFRQLPRCIYELERLETLSAHDNQIRAI 169
            |...||..||||:|.|..||.....|..||.|::|:|.|..:|.|::.|:.|..|....|::..|
Human   137 SLCRKLEVLSLSHNCLSQLPACFADLSRLRKLNLSNNFFAHIPMCVFSLKELIFLHVGSNRLENI 201

  Fly   170 DASESGLGGMR--------------------ELKRLNLGNNDIQIVPPILGKMQNLVELELWG-- 212
            ..|...|..::                    .|:.|||.|||||.:|..|..:..||.: .|.  
Human   202 AESIQHLASLQIFIAEGNNIHSFPRSLCLVTSLELLNLNNNDIQTLPSELHLLCRLVRI-AWNPM 265

  Fly   213 --------NPFRQPRHQILSMGTPALLSYLRTR 237
                    ||..:|..:::..|...|..||:.:
Human   266 DKGLHISHNPLSKPLPELVEGGLEMLFGYLKDK 298

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3494NP_611915.1 LRR <34..>231 CDD:227223 65/220 (30%)
leucine-rich repeat 38..62 CDD:275380 6/21 (29%)
leucine-rich repeat 63..86 CDD:275380 8/22 (36%)
LRR_4 85..124 CDD:289563 15/38 (39%)
leucine-rich repeat 87..109 CDD:275380 7/21 (33%)
leucine-rich repeat 110..133 CDD:275380 10/22 (45%)
leucine-rich repeat 134..155 CDD:275380 8/20 (40%)
leucine-rich repeat 156..181 CDD:275380 6/44 (14%)
leucine-rich repeat 182..204 CDD:275380 11/21 (52%)
LRRC30NP_001099051.1 LRR 1 72..93 6/16 (38%)
leucine-rich repeat 73..95 CDD:275380 6/18 (33%)
LRR_8 94..173 CDD:290566 30/82 (37%)
LRR 2 95..116 6/23 (26%)
leucine-rich repeat 96..118 CDD:275380 8/22 (36%)
LRR 3 118..139 7/20 (35%)
leucine-rich repeat 119..141 CDD:275380 7/21 (33%)
LRR_4 141..179 CDD:289563 17/37 (46%)
LRR 4 141..163 10/21 (48%)
leucine-rich repeat 142..164 CDD:275380 10/21 (48%)
LRR 5 164..185 8/20 (40%)
leucine-rich repeat 165..187 CDD:275380 9/21 (43%)
LRR 6 187..208 5/20 (25%)
leucine-rich repeat 188..210 CDD:275380 6/21 (29%)
LRR 7 210..231 0/20 (0%)
leucine-rich repeat 211..229 CDD:275380 0/17 (0%)
LRR 8 233..254 11/20 (55%)
leucine-rich repeat 257..277 CDD:275378 5/20 (25%)
LRR 9 265..287 3/21 (14%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165154188
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

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