DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3494 and Lrrc10

DIOPT Version :9

Sequence 1:	NP_611915.1	Gene:	CG3494 / 37903	FlyBaseID:	FBgn0035008	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	NP_001101566.1	Gene:	Lrrc10 / 314848	RGDID:	1307358	Length:	273	Species:	Rattus norvegicus

Alignment Length:	187	Identity:	61/187 - (32%)
Similarity:	91/187 - (48%)	Gaps:	7/187 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 DKYHMRNTRILQVSKAQISEVPMEVFEAAQQELVNIVSLDGNRLLEMPKDLPLLSEHLTQLVLNK 94
            |...|...|::.:|.:|:...|:.|  .:..|||.:. |..|.|..:|.||..| ::|..|.|:.
  Rat    24 DLREMPLDRMVDLSGSQLRRFPLHV--CSFTELVKLY-LSDNHLHSLPPDLAQL-QNLQILALDF 84

  Fly    95 NQISFVPTNISQYSKLTNLSLSNNLLCDLPMELGGLRLLRNLDISHNRFRQLPRCIYELERLETL 159
            |....:|..:....:|..|.|.||.|||||.||..|:.||.|.:..|...:||..:.||..|:||
  Rat    85 NNFKALPQAVCTLKQLCILYLGNNKLCDLPDELSLLQNLRTLWLESNCLTRLPDVVCELSLLKTL 149

  Fly   160 SAHDNQIRAIDASESGLGGMRELKRLNLGNNDIQIVPPILGKMQNLVELELWGNPFR 216
            .|..|.:|.:...   |..:|||:.:.|..|.:...|.:|..|..|..:::..|..|
  Rat   150 HAGSNALRLLPGQ---LRRLRELRTIWLSGNQLADFPSVLLHMPFLEVIDVDRNSIR 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3494	NP_611915.1	LRR	<34..>231	CDD:227223	60/183 (33%)
		leucine-rich repeat	38..62	CDD:275380	5/23 (22%)
		leucine-rich repeat	63..86	CDD:275380	8/22 (36%)
		LRR_4	85..124	CDD:289563	13/38 (34%)
		leucine-rich repeat	87..109	CDD:275380	5/21 (24%)
		leucine-rich repeat	110..133	CDD:275380	13/22 (59%)
		leucine-rich repeat	134..155	CDD:275380	7/20 (35%)
		leucine-rich repeat	156..181	CDD:275380	7/24 (29%)
		leucine-rich repeat	182..204	CDD:275380	6/21 (29%)
Lrrc10	NP_001101566.1	leucine-rich repeat	32..53	CDD:275380	5/22 (23%)
		LRR_8	52..110	CDD:290566	20/59 (34%)
		leucine-rich repeat	54..76	CDD:275380	9/23 (39%)
		leucine-rich repeat	77..99	CDD:275380	5/21 (24%)
		LRR_RI	<88..200	CDD:238064	38/114 (33%)
		leucine-rich repeat	100..122	CDD:275380	13/21 (62%)
		leucine-rich repeat	123..145	CDD:275380	8/21 (38%)
		leucine-rich repeat	146..168	CDD:275380	7/24 (29%)
		leucine-rich repeat	169..191	CDD:275380	6/21 (29%)
		leucine-rich repeat	192..213	CDD:275380	3/12 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000