DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3494 and Lrrc40

DIOPT Version :9

Sequence 1:	NP_611915.1	Gene:	CG3494 / 37903	FlyBaseID:	FBgn0035008	Length:	240	Species:	Drosophila melanogaster
Sequence 2:	XP_006233600.1	Gene:	Lrrc40 / 310946	RGDID:	1562017	Length:	602	Species:	Rattus norvegicus

Alignment Length:	202	Identity:	75/202 - (37%)
Similarity:	114/202 - (56%)	Gaps:	2/202 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 RILQVSKAQISEVPMEVFEAAQQELVNIVSLDGNRLLEMPKDLPLLSEHLTQLVLNKNQISFVPT 102
            ::|..|..|.:.:|.::|:|.:..:|..::...|:|.|:|:.:..|.|.:..:.|:.|::|.|..
  Rat   402 KLLDYSDKQATLIPDDIFDATKNTVVTSINFSKNQLCEIPQRIAELKEMVLDVNLSFNKLSLVSH 466

  Fly   103 NISQYSKLTNLSLSNNLLCDLPMELGGLRLLRNLDISHNRFRQLPRCIYELERLETLSAHDNQIR 167
            .:....||..|.|.||.|..||.|:..|..|:.:::|.|||:..|..:|.:..|||:...:||:.
  Rat   467 ELCLLQKLAFLDLRNNFLSSLPEEMSSLTKLQTINLSFNRFKVFPAVLYHISTLETILISNNQVG 531

  Fly   168 AIDASESGLGGMRELKRLNLGNNDIQIVPPILGKMQNLVELELWGNPFRQPRHQILSMGTPALLS 232
            ::|..:..|  |..|..|:|.|||:..:||.||....|..|.|.|||||.||..||..||.|:|.
  Rat   532 SVDPLKMKL--MENLSTLDLQNNDLLQIPPELGNCVQLRTLLLDGNPFRVPRAAILMKGTAAVLE 594

  Fly   233 YLRTRIP 239
            |||.|||
  Rat   595 YLRDRIP 601

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3494	NP_611915.1	LRR	<34..>231	CDD:227223	68/192 (35%)
		leucine-rich repeat	38..62	CDD:275380	6/23 (26%)
		leucine-rich repeat	63..86	CDD:275380	6/22 (27%)
		LRR_4	85..124	CDD:289563	12/38 (32%)
		leucine-rich repeat	87..109	CDD:275380	4/21 (19%)
		leucine-rich repeat	110..133	CDD:275380	10/22 (45%)
		leucine-rich repeat	134..155	CDD:275380	6/20 (30%)
		leucine-rich repeat	156..181	CDD:275380	8/24 (33%)
		leucine-rich repeat	182..204	CDD:275380	10/21 (48%)
Lrrc40	XP_006233600.1	leucine-rich repeat	84..106	CDD:275380
		PLN00113	89..>577	CDD:215061	58/176 (33%)
		leucine-rich repeat	107..129	CDD:275380
		leucine-rich repeat	130..152	CDD:275380
		leucine-rich repeat	153..175	CDD:275380
		leucine-rich repeat	176..221	CDD:275380
		leucine-rich repeat	222..244	CDD:275380
		leucine-rich repeat	245..266	CDD:275380
		leucine-rich repeat	267..290	CDD:275380
		leucine-rich repeat	291..313	CDD:275380
		leucine-rich repeat	427..473	CDD:275380	11/45 (24%)
		leucine-rich repeat	474..496	CDD:275380	10/21 (48%)
		leucine-rich repeat	497..519	CDD:275380	7/21 (33%)
		leucine-rich repeat	520..543	CDD:275380	8/24 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0472
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D295141at33208
OrthoFinder	1	1.000	-	-		FOG0005608
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820