DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3492 and CPR6

DIOPT Version :9

Sequence 1:	NP_611914.1	Gene:	CG3492 / 37902	FlyBaseID:	FBgn0035007	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	NP_013317.1	Gene:	CPR6 / 850914	SGDID:	S000004206	Length:	371	Species:	Saccharomyces cerevisiae

Alignment Length:	189	Identity:	41/189 - (21%)
Similarity:	78/189 - (41%)	Gaps:	41/189 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   243 LLRPQIYLDIEVREARIQGRLIIQLFTEACPQVVLEFMRICTQNNSSA------------IVFNR 295
            :.||:.:.||.: ..:.|||::.:|:.:..|:....|:::|..|...|            .:|:|
Yeast     1 MTRPKTFFDISI-GGKPQGRIVFELYNDIVPKTAENFLKLCEGNAGMAKTKPDVPLSYKGSIFHR 64

  Fly   296 ALAPIWME-----------GRLAMDPQRSTELTNIEHDFEVLNHGVDAGILSFPSRYVRGNARTA 349
            .:.....:           |....|.:...|...::||...|....:||          .|...:
Yeast    65 VIKDFMCQFGDFTNFNGTGGESIYDEKFEDENFTVKHDKPFLLSMANAG----------PNTNGS 119

  Fly   350 VNFTISFKPLSILNGRRIAFGKVRKG---MQLLERIQV-AVGHLPMSHNLISLTDCGVI 404
            ..| |:..|...|:|:.:.||:|.:|   ::|:|..|. ...:.|:..  :.:.||||:
Yeast   120 QAF-ITCVPTPHLDGKHVVFGEVIQGKRIVRLIENQQCDQENNKPLRD--VKIDDCGVL 175

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3492	NP_611914.1	cyclophilin	249..388	CDD:294131	34/165 (21%)
CPR6	NP_013317.1	cyclophilin_ABH_like	4..173	CDD:238907	37/182 (20%)
		TPR repeat	219..264	CDD:276809
		TPR repeat	269..303	CDD:276809
		TPR repeat	308..334	CDD:276809
		TPR_1	311..341	CDD:395414
		TPR repeat	342..368	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810