DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3492 and PUB49

DIOPT Version :9

Sequence 1:	NP_611914.1	Gene:	CG3492 / 37902	FlyBaseID:	FBgn0035007	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	NP_201554.1	Gene:	PUB49 / 836889	AraportID:	AT5G67530	Length:	595	Species:	Arabidopsis thaliana

Alignment Length:	414	Identity:	74/414 - (17%)
Similarity:	139/414 - (33%)	Gaps:	112/414 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 PYTMTNPVYNTHNPNLVGLDGQ--VEDSRPKHTFNVKRQELENNYRHHQRLIPVPTSRRTMPKIR 95
            |:|..: :....|||.|  ||:  ||....|:...:..:||:                    |:.
plant   149 PFTRAD-LITIQNPNAV--DGKVTVEFDHVKNGLKIDDEELK--------------------KMN 190

  Fly    96 SHIVMNEQRELYRQHRDRMSNIKGKVNTYL------PPPKVQIEGNGMELSYMEMLTAL------ 148
            |....|             .|:.|.:...|      ...::.:.|.|...:..|...|:
plant   191 SDPAYN-------------INVSGDIKHMLADLGTDKAKEIALHGGGGNKARNERAAAIAAILES 242

  Fly   149 ------YKKSNNTLRTFTKSPERLAAGRWRNANLAREKERRQLEKNKEFHKGGELFDPEAGKSKR 207
                  ..|:....:|::......|:...|:|:.|:.....:.......|..|   |.....||.
plant   243 RSKIKEVSKAEQPKQTYSVVDAASASVFGRSADAAKAGSSDKTAARIAMHMAG---DRTPVNSKM 304

  Fly   208 YKPK-SSGSFSCEIPMHVLHRYENLMDQCDVGVLCKLLRPQIYLDIEV--------REARIQ--- 260
            .|.: |||:.|...                   ......|....|.|:        ::..:|
plant   305 VKSRYSSGAASRSF-------------------TSSAFTPVTKNDFELIKVEKNPKKKGYVQFQT 350

  Fly   261 --GRLIIQLFTEACPQVVLEFMRICTQNNSSAIVFNRALAPIWMEGRLAMDPQRS--------TE 315
              |.|.|:|..:..|:....|:.:|.:...:.:.|:|::....::|.   ||..:        .:
plant   351 THGDLNIELHCDIAPRACENFITLCERGYYNGVAFHRSIRNFMIQGG---DPTGTGKGGESIWGK 412

  Fly   316 LTNIEHDFEVLNHGVDAGILSFPSRYVRGNARTAVNFTISFKPLSILNGRRIAFGKVRKGMQLLE 380
            ....|.:.::|:.|  .|::|..:   .|.......|.:.:|..:.||.:...||.|..|:..|
plant   413 PFKDEPNSKLLHSG--RGVVSMAN---SGPHTNGSQFFVLYKSATHLNYKHTVFGGVVGGLATL- 471

  Fly   381 RIQVAVGHLPMSHNLISLTDCGVI 404
               .|:.::|:..:...|.:..:|
plant   472 ---AAMENVPVDESDRPLEEIKII 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3492	NP_611914.1	cyclophilin	249..388	CDD:294131	31/159 (19%)
PUB49	NP_201554.1	RING	39..101	CDD:302633
PUB49	NP_201554.1	cyclophilin_RING	345..502	CDD:238904	32/160 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900