DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG3492 and Ppid

DIOPT Version :9

Sequence 1:NP_611914.1 Gene:CG3492 / 37902 FlyBaseID:FBgn0035007 Length:404 Species:Drosophila melanogaster
Sequence 2:NP_080628.1 Gene:Ppid / 67738 MGIID:1914988 Length:370 Species:Mus musculus


Alignment Length:186 Identity:44/186 - (23%)
Similarity:77/186 - (41%) Gaps:48/186 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   246 PQIYLDIEVREARIQGRLIIQLFTEACPQVVLEFMRICTQNNSSAIV-----------FNRALAP 299
            |:::.|:::...|: ||::::||.:..|:....|..:||....:...           |:|.:..
Mouse    16 PRVFFDVDIGGERV-GRIVLELFADIVPKTAENFRALCTGEKGTGSTTGKPLHFKGCPFHRIIKK 79

  Fly   300 IWMEGRLAMDPQRST------------ELTNIEHDFEVLNHGVDAGILSFPSRYVRGNARTAVN- 351
            ..::|. ....|..|            |..:.:||.|        |:||.      .||....| 
Mouse    80 FMIQGG-DFSNQNGTGGESIYGEKFEDENFHYKHDRE--------GLLSM------ANAGPNTNG 129

  Fly   352 --FTISFKPLSILNGRRIAFGKVRKGM---QLLERIQVAVGHLPMSHNLISLTDCG 402
              |.|:..|...|:|:.:.||:|.||:   :.||.::|. |..|.  .|..:.:||
Mouse   130 SQFFITTVPTPHLDGKHVVFGQVIKGLGVARTLENVEVN-GEKPA--KLCVIAECG 182

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3492NP_611914.1 cyclophilin 249..388 CDD:294131 38/167 (23%)
PpidNP_080628.1 cyclophilin_ABH_like 16..182 CDD:238907 42/184 (23%)
Chaperone activity. /evidence=ECO:0000250 185..215
Interaction with HSP90AB1. /evidence=ECO:0000250 214..370
TPR_11 223..304 CDD:290150
TPR repeat 223..251 CDD:276809
TPR repeat 272..302 CDD:276809
TPR_11 277..338 CDD:290150
TPR 277..306 CDD:197478
TPR repeat 307..335 CDD:276809
TPR_1 308..340 CDD:278916
TPR repeat 341..364 CDD:276809
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0652
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.