DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3492 and PPIC

DIOPT Version :9

Sequence 1:	NP_611914.1	Gene:	CG3492 / 37902	FlyBaseID:	FBgn0035007	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	NP_000934.1	Gene:	PPIC / 5480	HGNCID:	9256	Length:	212	Species:	Homo sapiens

Alignment Length:	172	Identity:	41/172 - (23%)
Similarity:	76/172 - (44%)	Gaps:	30/172 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   247 QIYLDIEVREARIQGRLIIQLFTEACPQVVLEFMRICTQNNS---SAIVFNRALAPIWMEGR--L 306
            :::.|:.:.:..: ||::|.||.:..|:.|..|:.:.|....   ....|:|.:....::|.  .
Human    39 KVFFDVRIGDKDV-GRIVIGLFGKVVPKTVENFVALATGEKGYGYKGSKFHRVIKDFMIQGGDIT 102

  Fly   307 AMDPQRSTEL---TNIEHDFEVLNHGVDAGILSFPSRYVRGNARTAVN---FTISFKPLSILNGR 365
            ..|......:   |..:.:|::.::|:  |.:|.      .||....|   |.|:....:.|:|:
Human   103 TGDGTGGVSIYGETFPDENFKLKHYGI--GWVSM------ANAGPDTNGSQFFITLTKPTWLDGK 159

  Fly   366 RIAFGKVRKGMQLLERI--QVAVGH-LPMSHNLISLTDCGVI 404
            .:.||||..||.::..|  |...|| .|       ||:|.:|
Human   160 HVVFGKVIDGMTVVHSIELQATDGHDRP-------LTNCSII 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3492	NP_611914.1	cyclophilin	249..388	CDD:294131	34/151 (23%)
PPIC	NP_000934.1	cyclophilin	39..197	CDD:294131	41/172 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11071
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.000