DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3492 and CG5071

DIOPT Version :9

Sequence 1:	NP_611914.1	Gene:	CG3492 / 37902	FlyBaseID:	FBgn0035007	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	NP_001303432.1	Gene:	CG5071 / 43090	FlyBaseID:	FBgn0039347	Length:	680	Species:	Drosophila melanogaster

Alignment Length:	378	Identity:	77/378 - (20%)
Similarity:	142/378 - (37%)	Gaps:	110/378 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 HQRLIPVPTSRRTMPKIRSHIV----MNEQRELYRQHRDRMSNIK-GKVNTYLPPPKVQIEGNGM 137
            |:.|.|.|   ..:|:.|..:|    .|..||:  :..|.:..|: .:..|...||   .:|:..
  Fly   354 HRNLTPDP---ELLPEPRRAVVPPHFNNSLREV--ELLDYVQQIELEQFRTLSQPP---YDGSHE 410

  Fly   138 ELSYMEMLTALYKKSN-----------NTLRTFTKSPERLAAGRWRNANLAREKERRQLEKNKEF 191
            ..|.....::...:||           ..:|...:.|::          :.:|::::|.:.::..
  Fly   411 SSSSPNSSSSTNSQSNYIALDTEYGLRELVRQLQQQPQQ----------VQQEQQQQQQQVHQLT 465

  Fly   192 HKGGELFDPEAGKSKRYKPKSSGSFSCEIPMHVLHRYENLMDQCDVGVLCKLL---RPQIYLDIE 253
            |   .::.|:|......:|:..|..|     |..||.:. .....|.::.:.:   .|..:||:|
  Fly   466 H---SIYQPDAILVNSVEPQLIGQQS-----HDHHRQDG-GTSSSVSIVRQPIVHCYPIYFLDME 521

  Fly   254 VREARIQGRLIIQLFTEACPQVVLEF-----------MRICTQNNSSAIVFNRALAPIWMEGRLA 307
            : ...:.||::|::.::|.|::...|           .|.||       ||.     .|....:
  Fly   522 I-AGELAGRVLIEVRSDAAPRMADNFGALVRHERGYGYRGCT-------VFQ-----AWGGESI- 572

  Fly   308 MDPQRSTELTNIEHDFEVLNHGVDAGILSFPSRYV-----------------RGNARTAVNFTIS 355
                       |..|||..|.  ..|..:|.|||.                 ||..|...:..:.
  Fly   573 -----------ITGDFESQNG--RGGHSAFESRYFLPDETGLPAHRGTVGMRRGQRRQDRSGFVG 624

  Fly   356 FKPLSILNGRR---IAFGKVRKGMQLLERIQV---AVGHLPMSHNLISLTDCG 402
            .:...:||..|   ..||.:.:|::|::||..   |:|. |...::|  .:||
  Fly   625 SQFRLVLNEMRSFTAIFGFIVQGIELVDRIAASGNALGR-PALRSII--RNCG 674

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3492	NP_611914.1	cyclophilin	249..388	CDD:294131	38/172 (22%)
CG5071	NP_001303432.1	RING	16..59	CDD:238093
CG5071	NP_001303432.1	cyclophilin	514..674	CDD:294131	42/189 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11071
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.000