DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3492 and ppig

DIOPT Version :9

Sequence 1:	NP_611914.1	Gene:	CG3492 / 37902	FlyBaseID:	FBgn0035007	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	NP_001001234.1	Gene:	ppig / 407915	XenbaseID:	XB-GENE-5805534	Length:	736	Species:	Xenopus tropicalis

Alignment Length:	189	Identity:	43/189 - (22%)
Similarity:	76/189 - (40%)	Gaps:	37/189 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   237 VGVLCKLLRPQIYLDIEVREARIQGRLIIQLFTEACPQVVLEFMRICTQNNS-----------SA 290
            :||  |:.|.:.:.||.:..|. .||::.:||::.||:....|..:||....           ..
Frog     1 MGV--KVQRTRCFFDIAINNAP-AGRVVFELFSDVCPKTCENFRSLCTGERGIGKSTQKPLHYKN 62

  Fly   291 IVFNRALAPIWMEGRLAMDPQR-----------STELTNIEHDFEVLNHGVDAGILSFPSRYVRG 344
            .:|:|.:....::|....:...           ..|..:|:|:.|.|        ||..:   ||
Frog    63 CMFHRVVKDFMIQGGDFSEGNGRGGESIYGGFFEDENFSIQHNKEFL--------LSMAN---RG 116

  Fly   345 NARTAVNFTISFKPLSILNGRRIAFGKVRKGMQLLERIQVAVGHLPMSHNL-ISLTDCG 402
            .......|.|:.||...|:|..:.||:|..|..|:..|:..........:: :|:.:||
Frog   117 KDTNGSQFFITTKPTPHLDGLHVVFGQVISGQDLVREIENQKTDASSKPSVDVSIQNCG 175

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3492	NP_611914.1	cyclophilin	249..388	CDD:294131	36/160 (23%)
ppig	NP_001001234.1	cyclophilin_ABH_like	9..175	CDD:238907	37/177 (21%)
ppig	NP_001001234.1	DUF4603	403..>563	CDD:292020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910