DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3492 and Ppil2

DIOPT Version :9

Sequence 1:	NP_611914.1	Gene:	CG3492 / 37902	FlyBaseID:	FBgn0035007	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	NP_001017383.1	Gene:	Ppil2 / 360746	RGDID:	1309484	Length:	521	Species:	Rattus norvegicus

Alignment Length:	366	Identity:	67/366 - (18%)
Similarity:	127/366 - (34%)	Gaps:	90/366 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 THNPNLVGL--DGQVEDSRPKHTFNVKRQELENNYRHHQRLIPVPTSRRTMPKIRSHIVMNEQRE 105
            |.|.::|.:  .|.|.........|:|.:.|.:      .|...|.||:.:      |.:.:...
  Rat   111 TDNTHIVAIRTTGNVYTYEAVEQLNIKAKNLRD------LLTDEPFSRQDI------ITLQDPTN 163

  Fly   106 LYRQHRDRMSNIKGKVNTYLP-------PPKVQIEGNGMELSYMEMLTALYK--KSNNTLRTFTK 161
            |.:.:.....::|..:....|       .|...::....|.  .|.|..|||  |.:..|....|
  Rat   164 LDKFNVSSFFHVKNNMRMIDPDEEKAKQDPSYYLKNTNAET--RETLQELYKEFKGDEILAATMK 226

  Fly   162 SPERLAAGRWRNANLAREKERRQLEKNKEFHKGGELFDPEAGKSKRYKPKSSGSFSCEIPMHVLH 226
            .||:              |:..||  |...:..|               |.|.||:....:....
  Rat   227 PPEK--------------KKVDQL--NAAHYSTG---------------KVSASFTSTAMVPETT 260

  Fly   227 RYENLMDQCDVGVLCKLLRPQIYLDIEVREARIQGRLIIQLFTEACPQVVLEFMRICTQNNSSAI 291
            ....::|: || :..:.::.:.|:.:...    :|.|.::|..:..|:....|:::|.:......
  Rat   261 HEAAVIDE-DV-LRYQFVKKKGYVRLHTN----KGDLNLELHCDLTPKTCENFIKLCKKQYYDGT 319

  Fly   292 VFNRALAPIWMEGRLAMDPQ--------------RSTELTNIEHDFEVLNHGVDAGILSFPSRYV 342
            :|:|::....::|.   ||.              :.....|:.|        ...|:||..:
  Rat   320 IFHRSIRNFVIQGG---DPTGTGTGGESYWGKPFKDEFRPNLSH--------TGRGVLSMAN--- 370

  Fly   343 RGNARTAVNFTISFKPLSILNGRRIAFGKVRKGMQLLERIQ 383
            .|.......|.|:|:..:.|:.:...||:|..|...|..::
  Rat   371 SGPNTNKSQFFITFRSCAYLDKKHTIFGRVVGGFDTLTAME 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3492	NP_611914.1	cyclophilin	249..388	CDD:294131	27/149 (18%)
Ppil2	NP_001017383.1	Ubox	42..96	CDD:128780
Ppil2	NP_001017383.1	cyclophilin_RING	281..440	CDD:238904	27/149 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900