Protein Alignment CG3492 and PPIL2

DIOPT Version :9

• Sequence 1: NP_611914.1
• Gene: CG3492 / 37902
• FlyBaseID: FBgn0035007
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: XP_011528343.1
• Gene: PPIL2 / 23759
• HGNCID: 9261
• Length: 616
• Species: Homo sapiens
• Alignment Length: 449
• Identity: 91/449 - (20%)
• Similarity: 153/449 - (34%)
• Gaps: 136/449 - (30%)

  Fly     6 DAPQASRGKIP--QIPSSMTPYVAAVKRGPYTMTNP---------------VYNTHNPNLVGLDG 53
            |.||.:..::|  ....|:.|:|       |.:..|               .|.|:..|...|||
Human    28 DLPQTNFRRLPFDHCSLSLQPFV-------YPVCTPDGIVFDLLNIVPWLKKYGTNPSNGEKLDG 85

  Fly    54 QVEDSRPKHTFNVKRQELENNYRHHQRLIPVPTSRRTMPKIRSHIV-MNEQRELYRQHRDRMSNI 117
            :   |..|..|:   :..|..| |...|..|.|:       .:||| :.....:|........||
Human    86 R---SLIKLNFS---KNSEGKY-HCPVLFTVFTN-------NTHIVAVRTTGNVYAYEAVEQLNI 136

  Fly   118 KGKVNTYLPPPKVQIEGNGMELSYMEMLT----------ALYKKSN-------------NTLRTF 159
            |.|                   ::.::||          .|...:|             |.::..
Human   137 KAK-------------------NFRDLLTDEPFSRQDIITLQDPTNLDKFNVSNFYHVKNNMKII 182

  Fly   160 TKSPERL---AAGRWRNANLAREKERRQLEKNKEFHKGGELF-----DPEAGKSKRYKP------ 210
            ....|:.   .:...:|.| |..:|..| |..||| ||.|:.     .||..|..:...
Human   183 DPDEEKAKQDPSYYLKNTN-AETRETLQ-ELYKEF-KGDEILAATMKAPEKKKVDKLNAAHYSTG 244

  Fly   211 KSSGSF-SCEIPMHVLHRYENLMDQCDVGVL-CKLLRPQIYLDIEVREARIQGRLIIQLFTEACP 273
            |.|.|| |..:.....|....:    |..|| .:.::.:.|:.:...    :|.|.::|..:..|
Human   245 KVSASFTSTAMVPETTHEAAAI----DEDVLRYQFVKKKGYVRLHTN----KGDLNLELHCDLTP 301

  Fly   274 QVVLEFMRICTQNNSSAIVFNRALAPIWMEGRLAMDPQ--------------RSTELTNIEHDFE 324
            :....|:|:|.::.....:|:|::....::|.   ||.              :.....|:.|
Human   302 KTCENFIRLCKKHYYDGTIFHRSIRNFVIQGG---DPTGTGTGGESYWGKPFKDEFRPNLSH--- 360

  Fly   325 VLNHGVDAGILSFPSRYVRGNARTAVNFTISFKPLSILNGRRIAFGKVRKGMQLLERIQ 383
                 ...||||..:.....|..   .|.|:|:..:.|:.:...||:|..|..:|..::
Human   361 -----TGRGILSMANSGPNSNRS---QFFITFRSCAYLDKKHTIFGRVVGGFDVLTAME 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3492	NP_611914.1	cyclophilin	249..388	CDD:294131	29/149 (19%)
PPIL2	XP_011528343.1	RING-Ubox_PPIL2	38..110	CDD:319577	19/85 (22%)
		RING_Ubox	100..159	CDD:388418	15/85 (18%)
		U-box domain, a modified RING finger	103..146	CDD:319361	11/68 (16%)
		cyclophilin_RING	281..440	CDD:238904	29/149 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900