DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3492 and AgaP_AGAP003265

DIOPT Version :9

Sequence 1:	NP_611914.1	Gene:	CG3492 / 37902	FlyBaseID:	FBgn0035007	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	XP_307775.3	Gene:	AgaP_AGAP003265 / 1269170	VectorBaseID:	AGAP003265	Length:	382	Species:	Anopheles gambiae

Alignment Length:	202	Identity:	42/202 - (20%)
Similarity:	66/202 - (32%)	Gaps:	76/202 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   246 PQIYLDIEVREARIQGRLIIQLFTEACPQVVLEFMRICTQNNSSAIVFNRALAPIWMEGRLAMDP 310
            |.:|||::|.|..: ||::|:|..:..|:....|..:||                   |...:.|
Mosquito    20 PLVYLDVKVGEESV-GRIVIELRADVVPRTAENFRALCT-------------------GERGIAP 64

  Fly   311 QRSTEL-----------------------------------TNIEHDFEVLNHGVDAGILSFPSR 340
            ...|.|                                   |..:.:|.:|:   :.|.:|..:
Mosquito    65 DTGTRLHYKGSPFHRVKSLFMSQGGDIVHFNGTGGESIYGKTFEDENFTLLH---EDGAVSMAN- 125

  Fly   341 YVRGNART-AVNFTISFKPLSILNGRRIAFGKVRKGMQLLERIQVAVGHLPMSHN-------LIS 397
              .|.|.| ...|.|:......|||..:..|.|.:|..:       ||.:....|       .|.
Mosquito   126 --LGKAHTNNSQFFITSGECPHLNGTNVVVGYVIRGGGI-------VGEMERHSNDDGDPLVPIV 181

  Fly   398 LTDCGVI 404
            :.|||.|
Mosquito   182 IEDCGQI 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3492	NP_611914.1	cyclophilin	249..388	CDD:294131	34/174 (20%)
AgaP_AGAP003265	XP_307775.3	TPR_11	289..350	CDD:290150
		TPR repeat	319..347	CDD:276809
		TPR_1	320..352	CDD:278916
		cyclophilin	20..186	CDD:294131	39/198 (20%)
		TPR repeat	282..314	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900