Protein Alignment CG3492 and PPIE

DIOPT Version :9

• Sequence 1: NP_611914.1
• Gene: CG3492 / 37902
• FlyBaseID: FBgn0035007
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_001181936.1
• Gene: PPIE / 10450
• HGNCID: 9258
• Length: 314
• Species: Homo sapiens
• Alignment Length: 251
• Identity: 50/251 - (19%)
• Similarity: 95/251 - (37%)
• Gaps: 65/251 - (25%)

  Fly   155 TLRTFTKSPERLAAGR----WRNANLAREKERRQLEKNKEFHKGGELFDPEAGKSKRYKPKSSGS 215
            |:|.....|.|:..|.    |.:.:..::...:.||:||| .:|.|   |...:::..:|.:..:
Human    76 TIRVNLAKPMRIKEGSSRPVWSDDDWLKKFSGKTLEENKE-EEGSE---PPKAETQEGEPIAKKA 136

  Fly   216 FSCEIPMHVLHRYENLMDQCDVGVLCKLLRPQIYLDIEVREARIQGRLIIQLFTEACPQVVLEFM 280
            .|                           .||:|:||::.. :..||:.:.|.::..|.....|.
Human   137 RS---------------------------NPQVYMDIKIGN-KPAGRIQMLLRSDVVPMTAENFR 173

  Fly   281 RICTQNNS---SAIVFNRALAPIWMEGRLAMDPQRSTELTN-------------IEHDFEVLNHG 329
            .:||....   ....|:|.:.....:|         .:.||             .:.:..:|.|
Human   174 CLCTHEKGFGFKGSSFHRIIPQFMCQG---------GDFTNHNGTGGKSIYGKKFDDENFILKH- 228

  Fly   330 VDAGILSFPSRYVRGNARTAVNFTISFKPLSILNGRRIAFGKVRKGMQLLERIQVA 385
            ...|:||..:   .|.......|.::......|:|:.:.||:|.:|:.:|.:|:||
Human   229 TGPGLLSMAN---SGPNTNGSQFFLTCDKTDWLDGKHVVFGEVTEGLDVLRQIEVA 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3492	NP_611914.1	cyclophilin	249..388	CDD:294131	32/153 (21%)
PPIE	NP_001181936.1	RRM	<5..>84	CDD:223796	2/7 (29%)
		RRM_PPIE	8..80	CDD:240793	2/3 (67%)
		cyclophilin_ABH_like	140..279	CDD:238907	31/152 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810