DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4563 and FADD

DIOPT Version :9

Sequence 1:	NP_611913.1	Gene:	CG4563 / 37901	FlyBaseID:	FBgn0035006	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_003815.1	Gene:	FADD / 8772	HGNCID:	3573	Length:	208	Species:	Homo sapiens

Alignment Length:	101	Identity:	24/101 - (23%)
Similarity:	46/101 - (45%)	Gaps:	21/101 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   443 IEQIIAELPEVEHVCVVGVRDARYGDAAGALIIKKEGAE---IADQKVIDHV-------AQRVVV 497
            :.:::|.|.  .|..:..|.|...|.||||    ..|.|   .|...:.|:|       |:::.|
Human    63 LRELLASLR--RHDLLRRVDDFEAGAAAGA----APGEEDLCAAFNVICDNVGKDWRRLARQLKV 121

  Fly   498 DYKQLNAGVIFVDKFPKNANGKVMRSLAREVFEKTK 533
            ...::::   ..|::|:|...:|..||  .:::.|:
Human   122 SDTKIDS---IEDRYPRNLTERVRESL--RIWKNTE 152

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4563	NP_611913.1	CaiC	21..531	CDD:223395	23/97 (24%)
CG4563	NP_611913.1	Firefly_Luc_like	49..521	CDD:213279	20/87 (23%)
FADD	NP_003815.1	DED_FADD	<24..82	CDD:260043	4/20 (20%)
		Death_FADD	97..181	CDD:260020	12/61 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	187..208
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.861654	Normalized mean entropy	S3005
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.950