DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4563 and AT1G20480

DIOPT Version :9

Sequence 1:	NP_611913.1	Gene:	CG4563 / 37901	FlyBaseID:	FBgn0035006	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_173472.1	Gene:	AT1G20480 / 838636	AraportID:	AT1G20480	Length:	565	Species:	Arabidopsis thaliana

Alignment Length:	553	Identity:	139/553 - (25%)
Similarity:	238/553 - (43%)	Gaps:	106/553 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 QVWSGPPRPT--VYDHNTSVGQIVF----NSLRCWP---TNVIQITDDDGTVLTNADMLAYATRI 71
            ::|.|..|..  :|......|.:|.    ||: .:|   .:|:.:    |.::|.|:.:..:..|
plant    79 ELWLGVERVAGCLYALGVRKGNVVIILSPNSI-LFPIVSLSVMSL----GAIITTANPINTSDEI 138

  Fly    72 ALFFKSEG-------LTQEDRVGIIANSSTFVIPVATACFFQATPFHAVNYSREPAIVQGLYSVT 129
            :   |..|       .|....|..:|.:|.|.:||..     ...:|..:.|         |.
plant   139 S---KQIGDSRPVLAFTTCKLVSKLAAASNFNLPVVL-----MDDYHVPSQS---------YG-- 184

  Fly   130 KPKIMFIDGPDYDRIKEITKEWSPKLITLTGKVEGVTSIEDLVKPHPAEKIYVPASLATGGDQIA 194
                        ||:|            |.|:      :|.:::..|:|.   ........|..|
plant   185 ------------DRVK------------LVGR------LETMIETEPSES---RVKQRVNQDDTA 216

  Fly   195 VVLCSSGTAGLPKAVALSHRHIAS------------TNSLCISTDVLYTSATIDWMTGFSITVMN 247
            .:|.||||.|..|.|.||||::.:            ..::|     ......|....||:..::.
plant   217 ALLYSSGTTGTSKGVMLSHRNLIALVQAYRARFGLEQRTIC-----TIPMCHIFGFGGFATGLIA 276

  Fly   248 LTCGFTRIISRRTFSAETALYLVSKYKVTCLAMAPWQAYELF--TSPLATSEQLESLKIAFVIGG 310
            |  |:|.::..: |.....|..|..::.:.|::.|.....:.  .:.:.:...|.||......|.
plant   277 L--GWTIVVLPK-FDMAKLLSAVETHRSSYLSLVPPIVVAMVNGANEINSKYDLSSLHTVVAGGA 338

  Fly   311 WISLALLRRAQELLPKTYVMFSYGTTETGVVTINIDHSLEC----SVGRLAPGMRIKIQGED-GQ 370
            .:|..:..:..|..||..::..||.||:..:..::.:..|.    :.|.|||.:..||...| |:
plant   339 PLSREVTEKFVENYPKVKILQGYGLTESTAIAASMFNKEETKRYGASGLLAPNVEGKIVDPDTGR 403

  Fly   371 QLGVNQTGEVLIDIGLKWEGYLSNPEDTATTL-QDGWINLGDLGYFDEDNNLYLVDRKKDLLKYK 434
            .||||||||:.|......:||..|.|.||:|: .:||:..|||.|.|.|..:::|||.|:|:|..
plant   404 VLGVNQTGELWIRSPTVMKGYFKNKEATASTIDSEGWLKTGDLCYIDGDGFVFVVDRLKELIKCN 468

  Fly   435 SKHYWPNEIEQIIAELPEVEHVCVVGVRDARYGDAAGALIIKKEGAEIADQKVIDHVAQRVVVDY 499
            .....|.|:|.::...||:....|:.:.|.:.|....|.|::|.|:.:::.:::..||:: |..|
plant   469 GYQVAPAELEALLLAHPEIADAAVIPIPDMKAGQYPMAYIVRKVGSNLSESEIMGFVAKQ-VSPY 532

  Fly   500 KQLNAGVIFVDKFPKNANGKVMRSLAREVFEKT 532
            |::.. |.|:...|||.:||::|   ||:.:.|
plant   533 KKIRK-VTFLASIPKNPSGKILR---RELTKLT 561

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4563	NP_611913.1	CaiC	21..531	CDD:223395	136/545 (25%)
CG4563	NP_611913.1	Firefly_Luc_like	49..521	CDD:213279	125/498 (25%)
AT1G20480	NP_173472.1	PLN02574	27..562	CDD:215312	139/553 (25%)
AT1G20480	NP_173472.1	4CL	43..557	CDD:213272	137/547 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920