Protein Alignment CG4563 and ACSBG2

DIOPT Version :10

• Sequence 1: NP_611913.1
• Gene: CG4563 / 37901
• FlyBaseID: FBgn0035006
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_112186.3
• Gene: ACSBG2 / 81616
• HGNCID: 24174
• Length: 666
• Species: Homo sapiens
• Alignment Length: 541
• Identity: 111/541 - (20%)
• Similarity: 181/541 - (33%)
• Gaps: 214/541 - (39%)

  Fly    33 VGQIVFNSLRCWPTNVIQITDDDGTVLTNADMLAYATRIALFFKSEGLTQEDRVGIIANSSTFVI 97
            ||.:.|||...:.|.|       |.:|..                 ||.    |||.|.:|
Human   108 VGILGFNSAEWFITAV-------GAILAG-----------------GLC----VGIYATNS---- 140

  Fly    98 PVATACFFQATPFHA-VNY------------------SREP--AIVQGLYSVTKPKIMFIDGPDY 141
              |..|.:..|  || ||.                  |.||  ||:|....:.|...::    .:
Human   141 --AEVCQYVIT--HAKVNILLVENDQQLQKILSIPQSSLEPLKAIIQYRLPMKKNNNLY----SW 197

  Fly   142 DRIKEITKEWSPKLITLTGKVEGVTSIEDLVKPHPAEKIYVPASLATGGDQIAVVLCSSGTAGLP 206
            |...|:            |:....|.:|.:::...|             :|.||::.:|||.|:|
Human   198 DDFMEL------------GRSIPDTQLEQVIESQKA-------------NQCAVLIYTSGTTGIP 237

  Fly   207 KAVALSHRHIASTNSLCISTDVLYTSATIDWMTGFSITVMNLTCGFTRIIS-------------- 257
            |.|.|||.:|.                   |:.|.......||.....::|
Human   238 KGVMLSHDNIT-------------------WIAGAVTKDFKLTDKHETVVSYLPLSHIAAQMMDI 283

  Fly   258 -------RRTFSAE------TALYLVSKYKVTCLAMAP--WQ-AYELFTSPLATSEQLESLKIAF 306
                   ..|:.|:      |.:..:.:.|.|.....|  |: .:|:.....|.|..|:  |.||
Human   284 WVPIKIGALTYFAQADALKGTLVSTLKEVKPTVFIGVPQIWEKIHEMVKKNSAKSMGLK--KKAF 346

  Fly   307 VIGGWI-SLALLRRAQELLPKTYVMFSYGTTETGV-----VTINIDH------------------ 347
            |   |. ::.....::::|.|.....||...:|.|     .::.:||
Human   347 V---WARNIGFKVNSKKMLGKYNTPVSYRMAKTLVFSKVKTSLGLDHCHSFISGTAPLNQETAEF 408

  Fly   348 --SLE--------------------------CSVGRLAPGMRIKI--QGEDGQQLGVNQTGEVLI 382
              ||:                          .|.|::..|.:..:  |.:||       .||:.:
Human   409 FLSLDIPIGELYGLSESSGPHTISNQNNYRLLSCGKILTGCKNMLFQQNKDG-------IGEICL 466

  Fly   383 DIGLKW-----EGYLSNPEDTATTLQD-GWINLGDLGYFDEDNNLYLVDRKKD-LLKYKSKHYWP 440
                 |     .|||.:..:|...:.| ||::.||||..|....||:....|: |:....::..|
Human   467 -----WGRHIFMGYLESETETTEAIDDEGWLHSGDLGQLDGLGFLYVTGHIKEILITAGGENVPP 526

  Fly   441 NEIEQII-AELPEVEHVCVVG 460
            ..:|.:: .::|.:.:..:||
Human   527 IPVETLVKKKIPIISNAMLVG 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4563	NP_611913.1	Firefly_Luc_like	49..521	CDD:341237	104/525 (20%)
ACSBG2	NP_112186.3	ACSBG_like	73..665	CDD:341256	111/541 (21%)