DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4563 and acsl3a

DIOPT Version :9

Sequence 1:	NP_611913.1	Gene:	CG4563 / 37901	FlyBaseID:	FBgn0035006	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_001038593.1	Gene:	acsl3a / 567157	ZFINID:	ZDB-GENE-050420-181	Length:	713	Species:	Danio rerio

Alignment Length:	561	Identity:	135/561 - (24%)
Similarity:	216/561 - (38%)	Gaps:	157/561 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 TDDDGTVLTNA---------------DMLAYATRIALFFKSEGLTQEDRVGIIANSSTFVIPVAT 101
            |.:||.|....               ::.|:.:.:|..    |......:.|...:....|..|.
Zfish   110 TQEDGKVFKKVILGEYRWMSYEQVFKEVNAFGSGLAAL----GQKPMKNIAIFCETRAEWIIAAQ 170

  Fly   102 ACFFQATPFHAVNYSR--EPAIVQGLYSV-------------TKPKIMFIDGPDYDRI-----KE 146
            |||....|...: ||.  .|||..||...             ||.|.:||:.|....:     |.
Zfish   171 ACFMYNFPLVTL-YSTLGGPAIAHGLNEAEVSHIITSKDLLETKLKSIFIEVPRLCHVIVVDDKL 234

  Fly   147 ITKEWSPKLITLTGKVEGVTSIEDL-VKPHPAEKIYVPASLATGGDQIAVVLCSSGTAGLPKAVA 210
            .|....|:.|:    :..:.|:::| .:|..|.|   |.:.....| :||::.:||:.|:||.|.
Zfish   235 STSSEYPRGIS----IHSMASVKELGARPENASK---PKNPPCSSD-VAVIMYTSGSTGVPKGVM 291

  Fly   211 LSHRHIAS-----TNSL--CISTD----------VLYTSATIDWMT-----GFSITVMNLTCGFT 253
            :||.:|.|     |:.:  .:..|          ||..||.:..:.     |:| :...|:...|
Zfish   292 ISHSNIISGITGMTHRIPKLVEDDTYIGYLPLAHVLELSAEMVCLAHGCRIGYS-SPQTLSDQST 355

  Fly   254 RI---------ISRRTFSA------------------------ETALYLVSKYKVTCLAMAPWQA 285
            :|         :.|.|..|                        .|...|...||:..|||.
Zfish   356 KIKKGSRGDISVLRPTLMAAVPEIMDRIYKNVMLRVEQMSGFQRTLFLLAYNYKMEQLAMG---- 416

  Fly   286 YELFTSPLATSEQLESLKIAFVIGGWISLALLRRAQELLPKTY----VMF------SYGTTET-G 339
               :::||.  ::|...|:..::||.:.: ||.....|...|.    :.|      .||.||| |
Zfish   417 ---YSTPLC--DKLVFRKVRALLGGRLRV-LLSGGAPLSAATQRFMNICFCCPVGQGYGLTETCG 475

  Fly   340 VVTINIDHSLECSVGRL-APGMRIKIQGEDGQQLGVNQT------GEVLIDIGLKWEGYLSNPED 397
            ..||:  |..:.|.||: ||.:..::|.:|..:.|.:.|      ||:|:.......||..|
Zfish   476 AGTIS--HLWDYSTGRVGAPLVCCELQLKDWIEGGYHSTDLPCPRGEILVGGPSITMGYYKN--- 535

  Fly   398 TATTLQD--------GWINLGDLGYFDEDNNLYLVDRKKDLLKYKSKHYWP-NEIEQIIAELPEV 453
            |..|.:|        .|...||:|....|..|.::||||||:|.::..|.. .::|..:...|.|
Zfish   536 THKTSEDFFVDKKGQRWFCTGDIGEIHGDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLV 600

  Fly   454 EHVCVVGVRDARYGDAAGALIIKKEGAEIADQKVIDHVAQR 494
            :::|.....|..|       :|   |..:.:||.:..:|:|
Zfish   601 DNICAYANSDESY-------VI---GFVVPNQKQLLALAER 631

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4563	NP_611913.1	CaiC	21..531	CDD:223395	135/561 (24%)
CG4563	NP_611913.1	Firefly_Luc_like	49..521	CDD:213279	135/561 (24%)
acsl3a	NP_001038593.1	PLN02387	77..710	CDD:215217	135/561 (24%)
acsl3a	NP_001038593.1	LC-FACS_euk	123..710	CDD:213293	131/548 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583074
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930