DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4563 and acsf3

DIOPT Version :9

Sequence 1:	NP_611913.1	Gene:	CG4563 / 37901	FlyBaseID:	FBgn0035006	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	XP_021329817.1	Gene:	acsf3 / 562292	ZFINID:	ZDB-GENE-121026-3	Length:	579	Species:	Danio rerio

Alignment Length:	593	Identity:	122/593 - (20%)
Similarity:	228/593 - (38%)	Gaps:	145/593 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 KETQVWSGPP----RPTVYDHNTSVGQIVFNSLRCWPTNVIQITDDDGTVLTNADMLAYATRIAL 73
            |...|:|..|    :..:.||:   |...::||                 ..|:.:||.....||
Zfish    51 KVAPVFSRAPAYGDKVAIMDHS---GSHTYHSL-----------------YKNSKILAGHITKAL 95

  Fly    74 FFKSEGLTQEDRVGII-ANSSTFVIP--VATACFFQATPFHAVNYSREP-AIVQGLYSVTKPKIM 134
            ..:| |..|..|:..: ||.:::.:.  .:..|...|.|.    |.:.| :.::.:.|.::..::
Zfish    96 TCQS-GDLQGKRISFLCANDASYTVAQWASWMCGGIAVPL----YRKHPLSELEYVISDSQSSLL 155

  Fly   135 FIDGPDYDRIKEITKEWS-P--KLITLTGKVEGVTSI-EDLVK---PHPAEKIYVPASLATGGDQ 192
            .......|.::.:.::.. |  ||...:.:.|...:: ||::.   ..||..||
Zfish   156 VAGQSFVDTLEPLAQKLGLPCLKLPATSSQFEDTQTLPEDMISDWAERPAMLIY----------- 209

  Fly   193 IAVVLCSSGTAGLPKAVALSHRHIASTNSLCIS------TDV--------------------LYT 231
                  :|||.|.||.|..:|..:.:.....:|      .||                    |:.
Zfish   210 ------TSGTTGRPKGVLHTHSSLQAMVQGLVSEWAWHKDDVILHTLPLHHVHGIVNKLMCPLWV 268

  Fly   232 SATIDWMTGFSITVM--NLTCGFTRIISRRTFSAETALY--LVSKYKVTCLAMAPWQAYELFTSP 292
            .||...:..||...:  .|.|..:.:::  .|.|...:|  |:..|.            :.||.|
Zfish   269 GATCIMLPDFSAQKVWEQLICSKSPMVN--VFMAVPTIYSKLIEYYD------------QHFTQP 319

  Fly   293 LATSEQLESL-------KIAFVIGGWISL--ALLRRAQELLPKTYVMFSYGTTETGVVTINI--D 346
                 |::..       :|..::.|..:|  .:|.|..|:.... ::..||.||.|:...|.  .
Zfish   320 -----QVQDFIRAVCKERIRLMVSGSAALPQPVLERWAEITDHV-LLERYGMTEIGMALSNSYKG 378

  Fly   347 HSLECSVGRLAPGMRIKIQGE------DGQQLGV-------NQTGEVLIDIGLKWEGYLSNPEDT 398
            ..:..:||...||:.::|...      :|...|.       .:.||:|:.....::.|.:.|::|
Zfish   379 PRVPGAVGVPLPGVEVRIMMNSSIVIAEGTSKGTQVKAGLEGKEGELLVRGSSVFQKYWNKPQET 443

  Fly   399 ATTL-QDGWINLGDLGYFDEDNNLYLVDRKK-DLLKYKSKHYWPNEIEQIIAELPEVEHVCVVGV 461
            ..:. :|.|...||...: .|...:::.|.. |::|.........::|:.:...|::..|.|:|.
Zfish   444 EESFTEDRWFKTGDTALY-RDGVYWIMGRTSVDIIKSGGYKISALDVERHLLAHPDITDVAVIGA 507

  Fly   462 RDARYGDAAGALIIKKEGAE--IADQK--VIDHVAQRVVVDYKQLNAGVIFVDKFPKNANGKV-M 521
            .||.:|....|::..::|..  ::|.|  ..:|:|.      ..:..|:|.|:..|:|..||| .
Zfish   508 PDATWGQKVTAVVQMRKGKTMILSDLKAWAREHMAS------YSIPTGLILVEDMPRNQMGKVNK 566

  Fly   522 RSLAREVF 529
            :.|.|:.|
Zfish   567 KDLLRQFF 574

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4563	NP_611913.1	CaiC	21..531	CDD:223395	119/585 (20%)
CG4563	NP_611913.1	Firefly_Luc_like	49..521	CDD:213279	110/543 (20%)
acsf3	XP_021329817.1	MCS	64..566	CDD:213307	115/570 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900