DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4563 and slc27a1a

DIOPT Version :9

Sequence 1:	NP_611913.1	Gene:	CG4563 / 37901	FlyBaseID:	FBgn0035006	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_001013555.1	Gene:	slc27a1a / 541410	ZFINID:	ZDB-GENE-050320-112	Length:	647	Species:	Danio rerio

Alignment Length:	506	Identity:	110/506 - (21%)
Similarity:	182/506 - (35%)	Gaps:	105/506 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 PTNVIQITDDDGTVLTNADMLAYATRIALFFKSEGLTQEDRVGIIANSSTFVIPVATACFF---- 105
            |..|.:.|.:..| .:..|.::.|  :|.:..|:|.|..|.|.:...|.    |:..|.:.
Zfish    93 PALVYEATGETWT-FSQLDQISNA--VAHWALSQGWTSGDVVALFMESR----PLQVALWLGLAK 150

  Fly   106 -------------QATPFHAVNYSREPAIVQGLYSVTKPKIMFIDGPDYDRIKEITKEWSPKLIT 157
                         :.:..|.|..|....||.|....             |.:.|::...|..::.
Zfish   151 VGVEAALINFNLRRDSLLHCVGVSASRGIVFGAELA-------------DAVSEVSHSLSQTMVR 202

  Fly   158 L-TGKVEGVTSIEDL---VKPHPAEKIYVPA-------SLATGGDQIAVVLCSSGTAGLPKAVAL 211
            . ||.::     .||   :|..|.:.|...|       :::.|.:.....:.:|||.|||||..:
Zfish   203 FSTGDLK-----PDLMAALKCQPLDPILASAPRHPPSCTVSKGFNDHLFYIYTSGTTGLPKAAIV 262

  Fly   212 SHR---HIASTNSLCI---STDVLYTSATIDWMTGFSITVMN----LTCGFTRIISRRTFSAETA 266
            .|.   .||:...|..   ..|::|....:....|   .:|.    |..|.| ::.:|.|||...
Zfish   263 VHSRYYRIAAFGYLSFRMRPDDIIYDCLPLYHSAG---NIMGVGQCLIHGLT-VVVKRKFSASRF 323

  Fly   267 LYLVSKYKVTCLAMAPWQAYELFTSPLATSEQLESLKIAFVIGGWISLALLRRAQELLPKTYVMF 331
            .....|:..|.:.........|...|:..||:...:::|  :|..:..::.....|......:..
Zfish   324 WEDCIKHNCTVVQYIGEICRYLLAQPVRPSERQHRVRLA--VGNGLRPSVWEAFVERFRVKQIGE 386

  Fly   332 SYGTTETGVVTINIDHSL-ECSV-GRLAPGM----RIKIQGE------DGQQLGVN-QTGEVLID 383
            .||.|.......|:|..: .|.. .|:.|.:    .:|:..|      |.|.|.|: :.||..:.
Zfish   387 FYGATGCNCSIANMDGKVGACGFNSRILPNVYPIRLVKVNEETMELVRDKQGLCVSCRPGEPGLL 451

  Fly   384 IG--------LKWEGYLSNPEDTATTL-------QDGWINLGDLGYFDEDNNLYLVDRKKDLLKY 433
            :|        .:::||.|. |.|...:       .|.....||:...||...:|..||..|..::
Zfish   452 VGRINQQDPLRRFDGYASQ-EATRKKIAYNVFRKNDSAYLSGDVLVMDELGYMYFRDRSGDTFRW 515

  Fly   434 KSKHYWPNEIEQIIAELPEVEHVCVVGVRDARYGDAAGALIIKKEGAEIAD 484
            |.::....|:|..::.|.....|.|.||........||.       |.|||
Zfish   516 KGENVSTTEVEGTLSGLLRQTDVAVFGVNVPGVEGKAGM-------AAIAD 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4563	NP_611913.1	CaiC	21..531	CDD:223395	110/506 (22%)
CG4563	NP_611913.1	Firefly_Luc_like	49..521	CDD:213279	108/502 (22%)
slc27a1a	NP_001013555.1	PRK08279	75..647	CDD:236217	110/506 (22%)
slc27a1a	NP_001013555.1	AFD_class_I	101..612	CDD:302604	107/498 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583004
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930