DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4563 and Fatp2

DIOPT Version :9

Sequence 1:	NP_611913.1	Gene:	CG4563 / 37901	FlyBaseID:	FBgn0035006	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_995925.2	Gene:	Fatp2 / 37657	FlyBaseID:	FBgn0265187	Length:	714	Species:	Drosophila melanogaster

Alignment Length:	564	Identity:	118/564 - (20%)
Similarity:	219/564 - (38%)	Gaps:	109/564 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 NTSVGQIVFNSLRCWPTNVIQITDDDGTVLTNADMLAYATRIALFFKSEGLTQEDRVG-IIANSS 93
            |.::|.|..:::...|..:..:::.........:  .::.|:|..|.|.|..:.|.|| ::.|.:
  Fly   138 NLNIGDIFESNVARQPDKLAIVSESQQWTFRQVN--EHSNRVANVFHSHGYKKGDVVGLLLENRA 200

  Fly    94 TFV------------IPVATACFFQATPFHAVNYSREPAIVQGLYSVTKPKIMFI--DGPDYDRI 144
            .||            .|:.......|:..|::...:..|::.|  :..:..:|.|  |.|.:..:
  Fly   201 EFVATWLGLSKIGVITPLINTNLRGASLQHSITVGQCTALIYG--ASFRSAVMDIAKDLPAHVGL 263

  Fly   145 KEITKEWSPKLITLTGKVEGVT-SIEDLVKPHPAEKIYVPASLATGGDQIAVVLCSSGTAGLPKA 208
            .:...|.:.:::...|..:|:. .:..|::....:|:...||.|...|:: |.:.:|||.|||||
  Fly   264 YQFNDESNQEVVASEGLSQGLAQQLNGLLETAAKDKVAAGASRADHHDKL-VYIYTSGTTGLPKA 327

  Fly   209 VALSHRH---IASTNSLCI---STDVLYTSATIDWMTGFSITVMN--LTCGFTRIISRRTFSAET 265
            ..::|..   ||:.....:   ..||.||...: :.|...:..|.  |..|.| ::.|:.|||..
  Fly   328 AVITHSRYFFIAAGIHYTLGFKDQDVFYTPLPL-YHTAGGVMSMGQALLFGST-VVIRKKFSASG 390

  Fly   266 ALYLVSKYKVTCLAMAPWQAYELFTSPLATSEQLESLKIAFVIGGWISLALLRRAQELLPKTYVM 330
            .....::::.|........|..:..:|.|..::...:::.|..|             |.|:.:..
  Fly   391 YFSDCARFQCTVGQYIGEMARYILATPSAPHDRNHQVRMVFGNG-------------LRPQIWPQ 442

  Fly   331 F-----------SYGTTETGVVTINIDHSLEC--SVGRLAPGMR----IKIQGEDGQQLGVNQ-- 376
            |           .||.||.....:|.|.::..  .:.|:.|.:.    ||.....|:.|..:|
  Fly   443 FVERFGIRKVGEFYGATEGNANIMNNDSTVGAIGFISRILPQIYPISIIKADPHTGEPLRNSQGL 507

  Fly   377 -----TGEVLIDIG--------LKWEGYLSNPEDTATTLQD-------GWINLGDLGYFDEDNNL 421
                 ..|..:.:|        .::.||:.....:...:.|       .:|: |||...||...|
  Fly   508 CERCEADEPGVFVGKIVRGNPCREFLGYVDQKASSKKVVHDVFSKGDMAFIS-GDLLVADERGYL 571

  Fly   422 YLVDRKKDLLKYKSKHYWPNEIEQIIAELPEVEHVCVVGV----RDARYGDAAGALIIKKEGAEI 482
            |..||..|..::|.::...:|:|..::.|...:.|.|.||    .:.|.|.||
  Fly   572 YFKDRTGDTFRWKGENVSTSEVEAQLSNLAGYKDVIVYGVSIPNTEGRAGMAA------------ 624

  Fly   483 ADQKVIDHVAQRVVVDYKQLNAGVIFVDKFPKNANGKVMRSLAR 526
                :.|...:   |:..||  ||......|..|..:.:|.|.:
  Fly   625 ----IYDPTRE---VNVSQL--GVELAKSLPNYARPQFLRFLRK 659

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4563	NP_611913.1	CaiC	21..531	CDD:223395	118/564 (21%)
CG4563	NP_611913.1	Firefly_Luc_like	49..521	CDD:213279	112/538 (21%)
Fatp2	NP_995925.2	PRK08279	115..714	CDD:236217	118/564 (21%)
Fatp2	NP_995925.2	AFD_class_I	163..680	CDD:302604	114/539 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452171
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840