Protein Alignment CG4563 and SLC27A1

DIOPT Version :9

• Sequence 1: NP_611913.1
• Gene: CG4563 / 37901
• FlyBaseID: FBgn0035006
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: XP_011526302.1
• Gene: SLC27A1 / 376497
• HGNCID: 10995
• Length: 658
• Species: Homo sapiens
• Alignment Length: 602
• Identity: 142/602 - (23%)
• Similarity: 218/602 - (36%)
• Gaps: 137/602 - (22%)

  Fly     8 PTFFNKETQVWSGPPRPTVYDHNTSVGQIVFNSLRCWPTNVIQITDDDGTVLTNADMLAYATRIA 72
            |..|  :..|...|.|..:.|..|.         .||               |.|.:.||:..:|
Human    79 PRIF--QAVVQRQPERLALVDAGTG---------ECW---------------TFAQLDAYSNAVA 117

  Fly    73 LFFKSEGLTQEDRVGI-IANSSTFV---IPVATACFFQATPFHAVNYSREP-AIVQGLYSVTKPK 132
            ..|:..|....|.|.| :.....||   :.:|.|....|  ...||..||| |...|   .:..|
Human   118 NLFRQLGFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAA--LLNVNLRREPLAFCLG---TSGAK 177

  Fly   133 IMFIDGPDYDRIKEITKEWSPKLITL-TGKV--EGVTSIEDLVKPHPAEKIYVPASL--ATGGDQ 192
            .:...|.....:.|::......||.. :|.:  ||:.....|:.|...|....|.:.  :.|.|.
Human   178 ALIFGGEMVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDTHLLDPLLKEASTAPLAQIPSKGMDD 242

  Fly   193 IAVVLCSSGTAGLPKAVALSHR---------HIASTNSLCISTDVLYTSATIDWMTGFSITV-MN 247
            ....:.:|||.|||||..:.|.         |.|....   :.||||....:....|..|.| ..
Human   243 RLFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRMQ---AADVLYDCLPLYHSAGNIIGVGQC 304

  Fly   248 LTCGFTRIISRRTFSAETALYLVSKYKVT----------CLAMAPWQAY------ELFTSPLATS 296
            |..|.| ::.|:.|||........||..|          ||.:    .|      .|...|:..:
Human   305 LIYGLT-VVLRKKFSASRFWDDCIKYNCTINGVRHCRLLCLVV----QYIGEICRYLLKQPVREA 364

  Fly   297 EQLESLKIAFVIGGWISLALLRRAQELLPKTYVMFSYGTTETGVVTINIDHSL-ECSVG------ 354
            |:...:::|  :|..:..|:.....|......:...||.||......|:|..: .|...
Human   365 ERRHRVRLA--VGNGLRPAIWEEFTERFGVRQIGEFYGATECNCSIANMDGKVGSCGFNSRILPH 427

  Fly   355 -----------------RLAPGMRIKIQ-GEDGQQLG-VNQTGEVLIDIGLKWEGYLSNPEDTAT 400
                             |.|.|:.|..| ||.|..:| :||.     |...:::||:|   ::||
Human   428 VYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVGQINQQ-----DPLRRFDGYVS---ESAT 484

  Fly   401 TLQ---------DGWINLGDLGYFDEDNNLYLVDRKKDLLKYKSKHYWPNEIEQIIAELPEVEHV 456
            :.:         |.....||:...||...:|..||..|..:::.::....|:|.:::.|.....|
Human   485 SKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEVEGVLSRLLGQTDV 549

  Fly   457 CVVGVR----DARYGDAAGALIIKKEGAEIADQKVIDHVAQRVVVDYKQLNAGVIFVDKFPK-NA 516
            .|.||.    :.:.|.||.|     :...:.|...|....|:|:..|    |..||:...|: :.
Human   550 AVYGVAVPGVEGKAGMAAVA-----DPHSLLDPNAIYQELQKVLAPY----ARPIFLRLLPQVDT 605

  Fly   517 NG--KVMRS-LAREVFE 530
            .|  |:.:: |.||.|:
Human   606 TGTFKIQKTRLQREGFD 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4563	NP_611913.1	CaiC	21..531	CDD:223395	139/589 (24%)
		Firefly_Luc_like	49..521	CDD:213279	129/549 (23%)
SLC27A1	XP_011526302.1	PRK08279	42..656	CDD:236217	142/602 (24%)
		metallo-hydrolase-like_MBL-fold	64..>135	CDD:304873	19/81 (23%)
		AFD_class_I	101..623	CDD:302604	135/578 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149007
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840