DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4563 and Acsm1

DIOPT Version :9

Sequence 1:	NP_611913.1	Gene:	CG4563 / 37901	FlyBaseID:	FBgn0035006	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_001101972.2	Gene:	Acsm1 / 361638	RGDID:	1306813	Length:	577	Species:	Rattus norvegicus

Alignment Length:	514	Identity:	120/514 - (23%)
Similarity:	197/514 - (38%)	Gaps:	104/514 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 LFFKSEGLTQEDRVGII--------------ANSSTFVIPVATACFFQATPFHAVNYSREPAIVQ 123
            :|.::.||...||:.:|              ..:....|| .||........:.:..|:..||
  Rat   101 VFEQTCGLQHGDRLALILPRVPEWWLVTVGCIRTGVIFIP-GTAQMKAKDILYRIQMSQAKAI-- 162

  Fly   124 GLYSVTKPKIMFIDGPDYDRIKEITKEWSPKLITLTGKVEGVTSIEDLVKPHPAEKIYVPASLAT 188
                ||...::    |:.:.:.........|::......||..:...|::....:...|.:.:.
  Rat   163 ----VTTDSLV----PEVESVASECPGLKTKIVVSDHNHEGWLNFRTLLRSASPDHTCVKSKMK- 218

  Fly   189 GGDQIAVVLCSSGTAGLPKAVALSHRHIASTNSL----------------CISTDVLYTSATI-- 235
              |.: |:..:|||.|.|| :|..::.:|..:|:                |:| |..:..||:
  Rat   219 --DPM-VIFFTSGTTGYPK-MAKHNQGLAFRSSVPSCRKFLKLKTSDVIWCMS-DPGWILATVGC 278

  Fly   236 ---DWMTGFSITVMNLTCGFTRIISRRTFSAETALYLVSKYKVT-CLAMAPWQAYELFTSPLATS 296
               .|..|.::.|.||.          .|..:..:..:.||.:| ||| || ..|.:......::
  Rat   279 LLEPWTAGATVFVHNLP----------QFDPKVIVETLFKYPITQCLA-AP-AVYRMVLQKNISN 331

  Fly   297 EQLESLKIAFVIGGWISLALLRRAQELLPKTYVMFS----------YGTTETGVVTINIDHSLEC 351
            .:..:|:.. ..||          :.|||:.|..:.          ||.:||| :|..|...::.
  Rat   332 LRFPTLEHC-ATGG----------ESLLPEEYEQWKQRTGLSIHEVYGQSETG-ITCAIFREMKV 384

  Fly   352 ---SVGRLAPGMRIKIQGEDGQQLGVNQTGEVLIDI------GLKWEGYLSNPEDTATTLQDGWI 407
               |:|:......|:|..|.|..|..|..|.:.|.|      || :.||.::||.|:......:.
  Rat   385 KRGSIGKAILPFDIQIIDEKGNILPPNTEGYIGIRIKPTRPLGL-FVGYENSPEKTSEVECGDFY 448

  Fly   408 NLGDLGYFDEDNNLYLVDRKKDLLKYKSKHYWPNEIEQIIAELPEVEHVCVVGVRDARYGDAAGA 472
            |.||....|||..::.:.|..|::........|.|:|..:.|.|.|....||...|...|:...|
  Rat   449 NSGDRATIDEDGYIWFLGRSDDVINASGYRIGPTEVENALVEHPAVSESAVVSSPDKDRGEVVKA 513

  Fly   473 LIIKKEGAEIADQKVI-----DHVAQRVVVDYKQLNAGVIFVDKFPKNANGKVMRSLAR 526
            .|:........||:.:     :|| :.|...||.... |.||.:.||...||:.|...|
  Rat   514 FIVLNPEFLSHDQEQLIKELQEHV-KSVTAPYKYPRK-VEFVSELPKTITGKIKRKELR 570

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4563	NP_611913.1	CaiC	21..531	CDD:223395	120/514 (23%)
CG4563	NP_611913.1	Firefly_Luc_like	49..521	CDD:213279	118/507 (23%)
Acsm1	NP_001101972.2	AFD_class_I	46..573	CDD:302604	120/514 (23%)
Acsm1	NP_001101972.2	Acs	46..570	CDD:223442	119/512 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010