DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4563 and Acsm4

DIOPT Version :9

Sequence 1:	NP_611913.1	Gene:	CG4563 / 37901	FlyBaseID:	FBgn0035006	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_859046.1	Gene:	Acsm4 / 353317	RGDID:	727928	Length:	580	Species:	Rattus norvegicus

Alignment Length:	485	Identity:	118/485 - (24%)
Similarity:	194/485 - (40%)	Gaps:	56/485 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 GLTQEDRVGIIANSSTFVIP----VATACFFQATPF--HAVNYSREPAIVQGLYSVTKPKIMFID 137
            ||.:.|||.:|...    ||    :..||......|  ..:..:|:..:.:  ...:|.|.:...
  Rat   110 GLQRGDRVAVILPR----IPEWWLINVACMRTGLVFMPGTIQLTRKDILYR--LQASKAKCIVAS 168

  Fly   138 ---GPDYDRIKEITKEWSPKLITLTGKVEGVTSIEDLVKPHPAEKIYVPASLATGGDQIAVVLCS 199
               .|..|.|.........||:....:.:|..|.::|::....|...|    .||..:...:..:
  Rat   169 EEVAPAVDSIASECPNLKTKLLVSPHRWDGWLSFQELLQSASEEHNCV----QTGSQEPMAIYFT 229

  Fly   200 SGTAGLPKAVALSHRHIASTNSLC-------ISTDVLYTSATIDWMTG-----FSITVMNLTCGF 252
            |||.|.||....|...:....:||       .|:|:::..:...|:..     || |.:...|.|
  Rat   230 SGTTGSPKMAQHSQSSLGIGYALCGRYWLDLTSSDIMWNMSDTGWIKAAIGSVFS-TWLRGACVF 293

  Fly   253 TRIISRRTFSAETALYLVSKYKVTCLAMAPWQAYELFTSPLATSEQLESLKIAFVIGGWISLALL 317
            ...:::  |:.:|.|..::.|.:|.|..|| ..|.:.........|.:.|:.....|..::..:|
  Rat   294 VHRMAQ--FNTDTFLDTLTSYPITTLCSAP-TVYRMLVQQDLKRYQFKRLRHCLTGGEPLNPEVL 355

  Fly   318 R--RAQELLPKTYVMFSYGTTETGVVTINIDHSLECSVGRLAPGM---RIKIQGEDGQQLGVNQT 377
            .  :||..|.   :...||.||.|::..| ....|...|.:..|:   .::|..|.|..|...:.
  Rat   356 EQWKAQTGLE---LYEGYGQTEVGIICAN-RKGEEIKPGSMGKGVVPYDVQIIDEHGNILPSGKE 416

  Fly   378 GEVLIDIGLK-----WEGYLSNPEDTATTLQDGWINLGDLGYFDEDNNLYLVDRKKDLLKYKSKH 437
            ||:.:.:|..     :..|:.|||.|..|::..:...||.|..|:|..|:.|.|..|::......
  Rat   417 GEIALRLGSDRPFCFFSEYVDNPEKTDATIRRNFYITGDRGVMDDDGYLWFVGRADDVIISSGYR 481

  Fly   438 YWPNEIEQIIAELPEVEHVCVVGVRDARYGDAAGALII-----KKEGAEIADQKVIDHVAQRVVV 497
            ..|.|:|..:.|.|.|....||...|...|:...|.|:     |....|....::.||| :....
  Rat   482 IGPFEVESALIEHPAVVESAVVSSPDPIRGEVVKAFIVLAAPFKSSNREKLTAELQDHV-KNSTA 545

  Fly   498 DYKQLNAGVIFVDKFPKNANGKVMRSLARE 527
            .||.... |.||.:.||...||:.|::.|:
  Rat   546 PYKYPRK-VEFVQELPKTITGKIKRNVLRD 574

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4563	NP_611913.1	CaiC	21..531	CDD:223395	118/485 (24%)
CG4563	NP_611913.1	Firefly_Luc_like	49..521	CDD:213279	116/477 (24%)
Acsm4	NP_859046.1	MACS_euk	48..577	CDD:341251	118/485 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920