DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4563 and Slc27a6

DIOPT Version :9

Sequence 1:	NP_611913.1	Gene:	CG4563 / 37901	FlyBaseID:	FBgn0035006	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_001099615.1	Gene:	Slc27a6 / 291582	RGDID:	1311977	Length:	619	Species:	Rattus norvegicus

Alignment Length:	498	Identity:	109/498 - (21%)
Similarity:	193/498 - (38%)	Gaps:	89/498 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 DGTVLTNADMLAYATRIA-LFFKSEGLTQEDRVGIIANSSTFVIPV--------ATACFFQA--- 107
            :|.|.|..|:...:.|:| .......|.:.|.|.::.::....:.|        ....|..:
  Rat    76 EGDVYTYEDVDKRSNRVAHALLNHSDLKRGDVVALLMSNEPDFVHVWFGLAKLGCVVAFLNSNLR 140

  Fly   108 --TPFHAVNYSREPAIVQGLYSVTKPKIMFIDGPDYDRIKEITKEWSPKLITLTGK----VEGVT 166
              :..|.:..|             :||.|.:.......::||... .||.|.:.|.    .||:.
  Rat   141 FESLLHCIRTS-------------EPKAMVVGEDLLGSLEEILPS-LPKHIRVWGMKDSVPEGIV 191

  Fly   167 SIEDLV-----KPHPAEKIYVPASLATGGDQIAVVLCSSGTAGLPKAVALSHRHIASTN-SL--- 222
            |:::.:     :|.|... :|.:||.:    ..:.:.:|||.|||||..:|...:...: .|
  Rat   192 SLKEKLSLASDEPVPPSH-HVTSSLKS----TCLYIFTSGTTGLPKAAVISQFQVLKGSFGLWAF 251

  Fly   223 -CISTDVLYTSATIDWMTGFSITV-----MNLTCGFTRIISRRTFSAETALYLVSKYKVTCLAMA 281
             |.:.|::|.:..:...:|..:.:     :..||     :.::.|||........||.||.....
  Rat   252 GCTADDIVYITLPLYHSSGALLGIGGCVELGATC-----VLKKKFSASQFWNDCRKYNVTVFQYI 311

  Fly   282 PWQAYELFTSPLATSEQLESLKIAFVIGGWISLALLRRAQELLPKTYVMFSYGTTETGVVTINID 346
            ......|...|....|:...:::|  :|..:|..:.|:..:......:...||.||..:..:|
  Rat   312 GELCRYLCKQPQREGEKDHRVRLA--VGNGMSSDVWRQFLDRFGNIKMCEFYGATEGNICFMN-- 372

  Fly   347 HSLEC-SVGR-------LAPGMRIK--------IQGEDGQQLGV--NQTGEVLIDIGLK--WEGY 391
            |:.:. ||||       |.....||        ::.|.|....|  .:.|.::..:..|  :.||
  Rat   373 HTGKIGSVGRVNFFYNLLFSFELIKYDFQKDEPLRNEQGWCYCVRKGEPGLLVSRVNKKNPFFGY 437

  Fly   392 LSNPEDTATTL-------QDGWINLGDLGYFDEDNNLYLVDRKKDLLKYKSKHYWPNEIEQIIAE 449
            ..:.:.|.:.|       .|.:.|.|||.:.|.:|.||..||..|..::|.::....|:..::..
  Rat   438 TGSYKQTKSKLLFDVFKKGDVYFNTGDLMFQDHENFLYFWDRIGDTFRWKGENVATTEVANVLGR 502

  Fly   450 LPEVEHVCVVGVRDARY-GDAAGALIIKKEGAEIADQKVIDHV 491
            |..::...|.||....| |.|....||.|....:..:|:.|.|
  Rat   503 LDFIQEANVYGVPVPGYEGKAGMTSIILKPNKSLDLEKMYDQV 545

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4563	NP_611913.1	CaiC	21..531	CDD:223395	109/498 (22%)
CG4563	NP_611913.1	Firefly_Luc_like	49..521	CDD:213279	109/498 (22%)
Slc27a6	NP_001099615.1	PRK08279	58..612	CDD:236217	109/498 (22%)
Slc27a6	NP_001099615.1	AFD_class_I	77..609	CDD:302604	109/497 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343010
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930