DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4563 and Slc27a2

DIOPT Version :9

Sequence 1:	NP_611913.1	Gene:	CG4563 / 37901	FlyBaseID:	FBgn0035006	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_036108.2	Gene:	Slc27a2 / 26458	MGIID:	1347099	Length:	620	Species:	Mus musculus

Alignment Length:	502	Identity:	114/502 - (22%)
Similarity:	188/502 - (37%)	Gaps:	99/502 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 LTNADMLAYATRIALFFKSE-GLTQEDRVGIIANSSTFVIPVATACFFQATPFHAVNYSREPAIV 122
            ||.|.:...:.::|.....: ||.|.|.|.:...:....:.:.........|...:||:.....:
Mouse    79 LTYAQVDRRSNQVARALHDQLGLRQGDCVALFMGNEPAYVWIWLGLLKLGCPMACLNYNIRAKSL 143

  Fly   123 QGLYSVTKPKIMFIDGPDYDRIKEITKEWSPKL---------ITLTGKVEGVTSIEDLV-----K 173
            ...:.....|:: :..||   ::|..:|..|.|         ::.|....||.:|.|.|     :
Mouse   144 LHCFQCCGAKVL-LASPD---LQEAVEEVLPTLKKDAVSVFYVSRTSNTNGVDTILDKVDGVSAE 204

  Fly   174 PHPAEKIYVPASLATGGDQIAVVLCSSGTAGLPKAVALSHRHIASTNSLCIST-----DVLYTSA 233
            |.| |......:..|.    ||.:.:|||.|||||..::|..:.....|.:|:     ||:||:.
Mouse   205 PTP-ESWRSEVTFTTP----AVYIYTSGTTGLPKAATINHHRLWYGTGLAMSSGITAQDVIYTTM 264

  Fly   234 TIDWMTGFSITVMNLTCGFTRIISRRTFSAETALYLVSKYKVTCLAMAPWQAYELFTSPLATSEQ 298
            .:.......|.:.........:..|..|||........||.||.:.........|..:|...:::
Mouse   265 PLYHSAALMIGLHGCIVVGATLALRSKFSASQFWDDCRKYNVTVIQYIGELLRYLCNTPQKPNDR 329

  Fly   299 LESLKIAFVIG--GWISLALLRRAQELLPKTYVMFSYGTTETGVVTINIDHSLECSVGRL----- 356
            ...:|.|...|  |.:....::|..::    :|...|.:||..:..:|....:. :|||.
Mouse   330 DHKVKKALGNGLRGDVWREFIKRFGDI----HVYEFYASTEGNIGFVNYPRKIG-AVGRANYLQR 389

  Fly   357 --------------------APGMRIKI-QGEDG------QQL--------GVNQT-GEVLIDIG 385
                                |.|..||: :||.|      .||        |..|| .:.|.|:.
Mouse   390 KVARYELIKYDVEKDEPVRDANGYCIKVPKGEVGLLVCKITQLTPFIGYAGGKTQTEKKKLRDVF 454

  Fly   386 LKWEGYLSNPEDTATTLQDGWINLGDLGYFDEDNNLYLVDRKKDLLKYKSKHYWPNEIEQIIAEL 450
            .|.:.|               .|.|||...|.:|.:|..||..|..::|.::....|:..|:..:
Mouse   455 KKGDIY---------------FNSGDLLMIDRENFVYFHDRVGDTFRWKGENVATTEVADIVGLV 504

  Fly   451 PEVEHVCVVGV----RDARYGDAAGALIIKKEGAEIADQKVIDHVAQ 493
            ..||.|.|.||    .:.|.|.|:..:   ||..|...:|:..|:|:
Mouse   505 DFVEEVNVYGVPVPGHEGRIGMASLKI---KENYEFNGKKLFQHIAE 548

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4563	NP_611913.1	CaiC	21..531	CDD:223395	114/502 (23%)
CG4563	NP_611913.1	Firefly_Luc_like	49..521	CDD:213279	114/502 (23%)
Slc27a2	NP_036108.2	hsFATP2a_ACSVL_like	74..610	CDD:341261	114/502 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839135
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930