Protein Alignment CG4563 and Acsf3

DIOPT Version :10

• Sequence 1: NP_611913.1
• Gene: CG4563 / 37901
• FlyBaseID: FBgn0035006
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_659181.2
• Gene: Acsf3 / 257633
• MGIID: 2182591
• Length: 583
• Species: Mus musculus
• Alignment Length: 568
• Identity: 128/568 - (22%)
• Similarity: 224/568 - (39%)
• Gaps: 116/568 - (20%)

  Fly    55 DGTVLTNADMLAYATRIALFFK--------------------------SEGLTQEDRVGIIANSS 93
            ||:|......||:..||||..|                          ..|..||:||..:.::.
Mouse    41 DGSVPVFIRALAFGDRIALIDKYGHHTYRELYDRSLCLAQEICRLQGCKVGDLQEERVSFLCSND 105

  Fly    94 TFVIPVATACFFQ---ATPFHAVNYSREPAIVQGLYSVTKPKIMFIDGPDY-DRIKEITKEWSPK 154
            ...:....|.:..   |.|.    |.:.|......:.......:.:.|.:| :|:..:.:.....
Mouse   106 VSYVVAQWASWMSGGVAVPL----YWKHPEAQLEYFIQDSRSSLVVVGQEYLERLSPLAQRLGVP 166

  Fly   155 LITLTGKV-EGVTSIEDLVKPHPAEKIYVPASLATGGDQIAVVLCSSGTAGLPKAVALSHRHIAS 218
            |:.||..| .|.|.       .|.|:   |...:...|:.|::..:|||.|.||....:||::|:
Mouse   167 LLPLTPAVYHGATE-------KPTEQ---PVEESGWRDRGAMIFYTSGTTGRPKGALSTHRNLAA 221

  Fly   219 TNSLCI------STDVLYTSATIDWMTGFSITVMNLTC----GFTRIISRRTFSAETA--LYLVS 271
            ..:..:      ..||:.....:..:.|   .|..|.|    |.|.::... |||:..  .:|.|
Mouse   222 VVTGLVHSWAWTKNDVILHVLPLHHVHG---VVNKLLCPLWVGATCVMLPE-FSAQQVWEKFLSS 282

  Fly   272 KYKVTCLAMAPWQAY--------ELFTSP------LATSEQLESLKIAFVIGGWISL--ALLRRA 320
            :.....:.||....|        :.||.|      .|..::    :|..::.|..:|  .||.:.
Mouse   283 EAPQITVFMAVPTVYSKLLDYYDKHFTQPHVQDFVRAVCKE----RIRLMVSGSAALPVPLLEKW 343

  Fly   321 QELLPKTYVMFSYGTTETGVVTIN--IDHSLECSVGRLAPGMRIKIQGE------------DGQQ 371
            :.....| ::..||.||.|:...|  .:..:..|||...||:.::|..|            :|.:
Mouse   344 RSATGHT-LLERYGMTEIGMALSNPLTEARVPGSVGTPLPGVEVRIISENPQKGSPYIIHAEGNE 407

  Fly   372 LGVNQT-------GEVLIDIGLKWEGYLSNPEDTATTL-QDGWINLGDLGYFDEDNNLYLVDRKK 428
            .|...|       ||:|:.....:..|...||:|.:.. .|||...||...| :|...::..|..
Mouse   408 RGTKVTPGFEEKEGELLVRGPSVFREYWDKPEETKSAFTSDGWFRTGDTAVF-KDARYWIRGRTS 471

  Fly   429 -DLLKYKSKHYWPNEIEQIIAELPEVEHVCVVGVRDARYGDAAGALIIKKEGAEIA--DQKVIDH 490
             |::|.........|||:.:...|.:..|.|:||.|..:|....|::..:||..::  |.|   .
Mouse   472 VDIIKTGGYKVSALEIERHLLAHPSITDVAVIGVPDMTWGQRVTAVVALQEGHSLSHGDLK---E 533

  Fly   491 VAQRVVVDYKQLNAGVIFVDKFPKNANGKV-MRSLAREVF---EKTKP 534
            .|:.|:..| .:.:.::.|::.|:|..||| .:.|.::::   ::::|
Mouse   534 WARGVLAPY-AVPSELLLVEEIPRNQMGKVNKKELLKQLYPSGQRSQP 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4563	NP_611913.1	Firefly_Luc_like	49..521	CDD:341237	126/550 (23%)
Acsf3	NP_659181.2	MCS	55..569	CDD:341264	122/541 (23%)