DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4563 and Acsl1

DIOPT Version :9

Sequence 1:	NP_611913.1	Gene:	CG4563 / 37901	FlyBaseID:	FBgn0035006	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_036952.1	Gene:	Acsl1 / 25288	RGDID:	2015	Length:	699	Species:	Rattus norvegicus

Alignment Length:	574	Identity:	127/574 - (22%)
Similarity:	209/574 - (36%)	Gaps:	163/574 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 ALFFKSEGLTQEDRVGIIANSSTFVIPVATACFFQATPFHAVNYSREPAIVQGLYS--------- 127
            ||..|......|..:||.:.:....:.:...||         .||   .:|..||.
  Rat   137 ALIQKGFKPCSEQFIGIFSQNRPEWVTIEQGCF---------TYS---MVVVPLYDTLGTDAITY 189

  Fly   128 -VTKPK--IMFIDGPDYDR--IKEITKEWSP--KLITLTG---------------KVEGVTSIED 170
             |.|.:  ::|.|.|:..:  ::.:..:.:|  |:|.:..               ::.|:.::||
  Rat   190 IVNKAELSVIFADKPEKAKLLLEGVENKLTPCLKIIVIMDSYDNDLVERGQKCGVEIIGLKALED 254

  Fly   171 L-----VKPHPAEKIYVPASLATGGDQIAVVLCSSGTAGLPKAVALSHRH--------IASTNSL 222
            |     .||.|.|.           :.:|::..:|||.|.||...::|::        |.:|.|.
  Rat   255 LGRVNRTKPKPPEP-----------EDLAIICFTSGTTGNPKGAMVTHQNIMNDCSGFIKATESA 308

  Fly   223 CIST--DVLYT-------------------SATIDWMTG----------------FSITVMNLTC 250
            .|::  |||.:                   .|.|.:..|                |.:....|..
  Rat   309 FIASPEDVLISFLPLAHMFETVVECVMLCHGAKIGFFQGDIRLLMDDLKVLQPTIFPVVPRLLNR 373

  Fly   251 GFTRIISRRTFSAET-ALYLVSKYKVTCLAMAPWQAYELFTSPLATSEQLESL---KIAFVIGGW 311
            .|.||..:...|.:. .|...||.|..          ||.:..:..:...:.|   ||...:||.
  Rat   374 MFDRIFGQANTSVKRWLLDFASKRKEA----------ELRSGIVRNNSLWDKLIFHKIQSSLGGK 428

  Fly   312 ISLALLRRAQELLPKTYVMF-----------SYGTTE-TGVVTINIDHSLECS-VGRLAPGMRIK 363
            :.|.:...|.  :..|.:.|           .||.|| |....:::....... ||...|...||
  Rat   429 VRLMITGAAP--VSATVLTFLRAALGCQFYEGYGQTECTAGCCLSLPGDWTAGHVGAPMPCNYIK 491

  Fly   364 -IQGEDGQQLGVNQTGEVLIDIGLKWEGYLSNPEDTATTL-QDGWINLGDLGYFDEDNNLYLVDR 426
             :..||.........|||.:.....::|||.:|..||..| :|||::.||:|.:..:..|.::||
  Rat   492 LVDVEDMNYQAAKGEGEVCVKGANVFKGYLKDPARTAEALDKDGWLHTGDIGKWLPNGTLKIIDR 556

  Fly   427 KKDLLKYKSKHY-WPNEIEQIIAELPEVEHVCVVGVRDARYGDAAGALIIKKEGAEIADQKVIDH 490
            ||.:.|.....| .|.:||.|......|..|.|       :|::..|.:|   ...:.|.:::..
  Rat   557 KKHIFKLAQGEYIAPEKIENIYLRSEAVAQVFV-------HGESLQAFLI---AIVVPDVEILPS 611

  Fly   491 VAQR--------VVVDYKQLNAGVI-FVDKFPKNANGKVMRSLAREVFEKTKPI 535
            .||:        .:...|.:|..:: .:.|..|||..|        .||:.|.|
  Rat   612 WAQKRGFQGSFEELCRNKDINKAILEDMVKLGKNAGLK--------PFEQVKGI 657

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4563	NP_611913.1	CaiC	21..531	CDD:223395	124/568 (22%)
CG4563	NP_611913.1	Firefly_Luc_like	49..521	CDD:213279	123/558 (22%)
Acsl1	NP_036952.1	LC-FACS_euk	117..695	CDD:341250	127/574 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342965
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930