Protein Alignment CG4563 and ACSL6

DIOPT Version :10

• Sequence 1: NP_611913.1
• Gene: CG4563 / 37901
• FlyBaseID: FBgn0035006
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_056071.2
• Gene: ACSL6 / 23305
• HGNCID: 16496
• Length: 722
• Species: Homo sapiens
• Alignment Length: 592
• Identity: 120/592 - (20%)
• Similarity: 194/592 - (32%)
• Gaps: 171/592 - (28%)

  Fly    75 FKSEGLTQ-------EDRVGIIANSSTFVIPVATACFFQATPFHAVNYSREPAIVQGLYSVTKPK 132
            |...||.|       :..:|:.|.:....|.|..||:..:.....:..:..|..::.:.:.....
Human   157 FLGSGLLQHNCKACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIINTADIS 221

  Fly   133 IMFIDGPD----------------------YDRIKEITKEWSPKLITLTGKVEGVTSIEDL---- 171
            .:.:|.|.                      .|..:|..||...|...:   ::.:.::||.
Human   222 TVIVDKPQKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQKCGVV---IKSMQAVEDCGQEN 283

  Fly   172 ----VKPHPAEKIYVPASLATGGDQIAVVLCSSGTAGLPKAVALSHRH-IASTNSLCISTDVLYT 231
                |.|.|              |.:::|..:|||.|.||...|:|.: :|..:.....|:..:.
Human   284 HQAPVPPQP--------------DDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTESQWA 334

  Fly   232 SATIDWMTGFSITVMNLTCGFTRII--------SRRTFSAETALYLVSKYKVTCLAMAPW----- 283
            ....|    ..|:.:.|...|.|::        .|..|.......|....|..|..:.|.
Human   335 PTCAD----VHISYLPLAHMFERMVQSVVYCHGGRVGFFQGDIRLLSDDMKALCPTIFPVVPRLL 395

  Fly   284 -----QAYELFTSPL--------ATSEQLE---------SL-------KIAFVIGGWIS------ 313
                 :.:....:||        |..:|.|         |:       ||...:||.:.
Human   396 NRMYDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGA 460

  Fly   314 -------LALLRRAQELLPKTYVMFSYGTTE--TGVVTINIDHSLECSVGRLAPGMRIK-IQGED 368
                   |..||.|.    ...|...||.||  .|.............||...|...|| :..|:
Human   461 APASPTVLGFLRAAL----GCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEE 521

  Fly   369 GQQLGVNQTGEVLIDIGLKWEGYLSNPEDTATTL-QDGWINLGDLGYFDEDNNLYLVDRKKDLLK 432
            .........||:.:.....::|||.:|:.|...| .|||::.||:|.:.....|.::||||.:.|
Human   522 LNYWACKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFK 586

  Fly   433 YKSKHY-WPNEIEQIIAELPEVEHVCVVGVRDARYGDAAGALIIKKEGAEIADQKVIDHVAQRVV 496
            .....| .|.:||.|......|..:.|       :||:..|.::   |..:.|.:|:...||:..
Human   587 LAQGEYVAPEKIENIYIRSQPVAQIYV-------HGDSLKAFLV---GIVVPDPEVMPSWAQKRG 641

  Fly   497 VD-------------------------------YKQLNAGVIFVDKFPKNANG------KVMRSL 524
            ::                               ::|:.|..|..|.|... ||      |..|..
Human   642 IEGTYADLCTNKDLKKAILEDMVRLGKESGLHSFEQVKAIHIHSDMFSVQ-NGLLTPTLKAKRPE 705

  Fly   525 AREVFEK 531
            .||.|:|
Human   706 LREYFKK 712

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4563	NP_611913.1	Firefly_Luc_like	49..521	CDD:341237	115/580 (20%)
ACSL6	NP_056071.2	LC-FACS_euk	141..719	CDD:341250	120/592 (20%)