Protein Alignment CG4563 and ACSL4

DIOPT Version :10

• Sequence 1: NP_611913.1
• Gene: CG4563 / 37901
• FlyBaseID: FBgn0035006
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_075266.1
• Gene: ACSL4 / 2182
• HGNCID: 3571
• Length: 711
• Species: Homo sapiens
• Alignment Length: 502
• Identity: 119/502 - (23%)
• Similarity: 200/502 - (39%)
• Gaps: 150/502 - (29%)

  Fly    79 GLTQEDRVGIIANSSTFVIPVATACF---FQATPFHAVNYSREPAIVQGL------YSVTKPK-- 132
            ||..::.:.|...:....:..|..||   |.....:| ...:| |:|.||      |.:|..:
Human   146 GLKPKNTIAIFCETRAEWMIAAQTCFKYNFPLVTLYA-TLGKE-AVVHGLNESEASYLITSVELL 208

  Fly   133 ----------------IMFIDGPDYDRIKEITKEWSPKLITLTGKVEGVTSIEDLVKPHPAEKIY 181
                            |:::|.      |.|.|...|:..    ::..:.|:|:| ..:| |.:.
Human   209 ESKLKTALLDISCVKHIIYVDN------KAINKAEYPEGF----EIHSMQSVEEL-GSNP-ENLG 261

  Fly   182 VPASLATGGDQIAVVLCSSGTAGLPKAVALSHRH-IASTNSLCIS----------------TDVL 229
            :|.|..|..| :|:|:.:||:.|.||.|.:.|.: ||.....|..                ..||
Human   262 IPPSRPTPSD-MAIVMYTSGSTGRPKGVMMHHSNLIAGMTGQCERIPGLGPKDTYIGYLPLAHVL 325

  Fly   230 YTSATIDWMT-----GFSITVMNLTCGFTRIISRRTFSAETA-LYLVSK-----YKVTCLAMAPW 283
            ..:|.|...|     |:|              |..|.|.::: :...||     .|.|.:|..|.
Human   326 ELTAEISCFTYGCRIGYS--------------SPLTLSDQSSKIKKGSKGDCTVLKPTLMAAVPE 376

  Fly   284 QAYELFTSPLATSEQLESL-KIAFVIG----------GW----ISLALLRRAQELL--------- 324
            ....::.:.::..:::..: |..|.||          |:    .:|.|.::.:.||
Human   377 IMDRIYKNVMSKVQEMNYIQKTLFKIGYDYKLEQIKKGYDAPLCNLLLFKKVKALLGGNVRMMLS 441

  Fly   325 ------PKTY----VMF------SYGTTET---GVVTINIDHSLECSVGRL-APGMRIKIQGEDG 369
                  |:|:    |.|      .||.||:   |.||...|:    :.||: ||.:..:|:.:|.
Human   442 GGAPLSPQTHRFMNVCFCCPIGQGYGLTESCGAGTVTEVTDY----TTGRVGAPLICCEIKLKDW 502

  Fly   370 QQLGV------NQTGEVLI---DIGLKWEGYLSNPEDTA---TTLQDG--WINLGDLGYFDEDNN 420
            |:.|.      |..||::|   :|.:   ||..|.|.||   :..::|  |...||:|.|..|..
Human   503 QEGGYTINDKPNPRGEIVIGGQNISM---GYFKNEEKTAEDYSVDENGQRWFCTGDIGEFHPDGC 564

  Fly   421 LYLVDRKKDLLKYKSKHYWP-NEIEQIIAELPEVEHVCVVGVRDARY 466
            |.::||||||:|.::..|.. .::|..:...|.::::|.....|..|
Human   565 LQIIDRKKDLVKLQAGEYVSLGKVEAALKNCPLIDNICAFAKSDQSY 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4563	NP_611913.1	Firefly_Luc_like	49..521	CDD:341237	119/502 (24%)
ACSL4	NP_075266.1	LC_FACS_euk1	121..696	CDD:341294	119/502 (24%)