Protein Alignment CG4563 and ACSL3

DIOPT Version :10

• Sequence 1: NP_611913.1
• Gene: CG4563 / 37901
• FlyBaseID: FBgn0035006
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_004448.2
• Gene: ACSL3 / 2181
• HGNCID: 3570
• Length: 720
• Species: Homo sapiens
• Alignment Length: 516
• Identity: 115/516 - (22%)
• Similarity: 198/516 - (38%)
• Gaps: 132/516 - (25%)

  Fly    79 GLTQEDRVGIIANSSTFVIPVATACF---FQATPFHAVNYSREPAIVQGLYSVTKPKIMFIDGPD 140
            |...:..:.|...:....:..|.|||   ||....:|.  ...||||..|.......|:......
Human   155 GQKPKTNIAIFCETRAEWMIAAQACFMYNFQLVTLYAT--LGGPAIVHALNETEVTNIITSKELL 217

  Fly   141 YDRIKEITKEWSPKL---ITLTGK------------VEGVTSIEDL-----------VKPHPAEK 179
            ..::|:|. ...|:|   ||:.||            |..:.::|.|           .||.|::
Human   218 QTKLKDIV-SLVPRLRHIITVDGKPPTWSEFPKGIIVHTMAAVEALGAKASMENQPHSKPLPSD- 280

  Fly   180 IYVPASLATGGDQIAVVLCSSGTAGLPKAVALSHRHI---------------------------- 216
                         |||::.:||:.||||.|.:||.:|
Human   281 -------------IAVIMYTSGSTGLPKGVMISHSNIIAGITGMAERIPELGEEDVYIGYLPLAH 332

  Fly   217 ---ASTNSLCISTDVLYTSATIDWMTGFSITVMNLTCGFTRIISRRTFSAETALYLVSKYKVTCL 278
               .|...:|:|.......::...:...|..:...:.|.|.:: :.|..|.....:...||....
Human   333 VLELSAELVCLSHGCRIGYSSPQTLADQSSKIKKGSKGDTSML-KPTLMAAVPEIMDRIYKNVMN 396

  Fly   279 AMAPWQAYELFTSPLATSEQLESL---------------KIAFVIGGWISLALLRRAQELLPKTY 328
            .::...:::.....||.:.::|.:               |:..::||.|.|.|...|.  |..|.
Human   397 KVSEMSSFQRNLFILAYNYKMEQISKGRNTPLCDSFVFRKVRSLLGGNIRLLLCGGAP--LSATT 459

  Fly   329 VMF-----------SYGTTET-GVVTINIDHSLECSVGRL-APGMRIKIQGEDGQQLGVNQT--- 377
            ..|           .||.||: |..||:  ...:.:.||: ||.:..:|:.::.::.|...|
Human   460 QRFMNICFCCPVGQGYGLTESAGAGTIS--EVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKP 522

  Fly   378 ---GEVLIDIGLKWEGYLSNPEDT-ATTLQD----GWINLGDLGYFDEDNNLYLVDRKKDLLKYK 434
               ||:||.......||..|...| |...:|    .|:..||:|.|:.|..|.::||||||:|.:
Human   523 HPRGEILIGGQSVTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQ 587

  Fly   435 SKHYWP-NEIEQIIAELPEVEHVCVVGVRDARYGDAAGALIIKKEGAEIADQKVIDHVAQR 494
            :..|.. .::|..:..||.|:::|.       |.::..:.:|   |..:.:||.:..:|::
Human   588 AGEYVSLGKVEAALKNLPLVDNICA-------YANSYHSYVI---GFVVPNQKELTELARK 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4563	NP_611913.1	Firefly_Luc_like	49..521	CDD:341237	115/516 (22%)
ACSL3	NP_004448.2	Adenylate forming domain, Class I superfamily	30..717	CDD:473059	115/516 (22%)