Protein Alignment CG4563 and ACSF3

DIOPT Version :9

• Sequence 1: NP_611913.1
• Gene: CG4563 / 37901
• FlyBaseID: FBgn0035006
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: XP_005256350.1
• Gene: ACSF3 / 197322
• HGNCID: 27288
• Length: 610
• Species: Homo sapiens
• Alignment Length: 541
• Identity: 123/541 - (22%)
• Similarity: 207/541 - (38%)
• Gaps: 152/541 - (28%)

  Fly    52 TDDDGTVLTNADMLAYATRIA------------LFFKSEGLTQ--------------EDRVGII- 89
            :|....|.|.|  ||:..|||            |:.:|..|:|              |:||..:
Human    40 SDRSAPVFTRA--LAFGDRIALVDQHGRHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLC 102

  Fly    90 ANSSTFVIPVATACFFQ---ATPFHAVNYSREPAIVQGLYSV--TKPKIMFIDGPDYDRIKEITK 149
            ||.:::|: ...|.:..   |.|.    |.:.|| .|..|.:  ::..::.......:.:..:.:
Human   103 ANDASYVV-AQWASWMSGGVAVPL----YRKHPA-AQLEYVICDSQSSVVLASQEYLELLSPVVR 161

  Fly   150 EWSPKLITL-----TGKVEGVTSIEDLVKPHPAEKIYVPASLATGGDQIAVVLCSSGTAGLPKAV 209
            :....|:.|     ||.||           .|||   ||.......::.|:::.:|||.|.||.|
Human   162 KLGVPLLPLTPAIYTGAVE-----------EPAE---VPVPEQGWRNKGAMIIYTSGTTGRPKGV 212

  Fly   210 ALSHRHIASTNS------------------------------LCISTDVLYTSATIDWMTGFSIT 244
            ..:|::|.:..:                              ||    .|:..||...|..||..
Human   213 LSTHQNIRAVVTGLVHKWAWTKDDVILHVLPLHHVHGVVNALLC----PLWVGATCVMMPEFSPQ 273

  Fly   245 VMNLTCGFTRIISRRT-----FSAETALY--LVSKYKVTCLAMAPWQAYELFTSPLATSEQLESL 302
            .:     :.:.:|..|     |.|...:|  |:..|.            ..||.|.| .:.|.::
Human   274 QV-----WEKFLSSETPRINVFMAVPTIYTKLMEYYD------------RHFTQPHA-QDFLRAV 320

  Fly   303 ---KIAFVIGGWISLAL--LRRAQELLPKTYVMFSYGTTETGVV---TINIDHSLECSVGRLAPG 359
               ||..::.|..:|.|  |.:.:.:...| ::..||.||.|:.   .:.....|..|||...||
Human   321 CEEKIRLMVSGSAALPLPVLEKWKNITGHT-LLERYGMTEIGMALSGPLTTAVRLPGSVGTPLPG 384

  Fly   360 MRIKIQGE-------------DGQQLGVNQT-------GEVLIDIGLKWEGYLSNPEDT--ATTL 402
            ::::|..|             :|.:.|...|       ||:|:.....:..|.:.||:|  |.||
Human   385 VQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGELLVRGPSVFREYWNKPEETKSAFTL 449

  Fly   403 QDGWINLGDLGYFDEDNNLYLVDRKK-DLLKYKSKHYWPNEIEQIIAELPEVEHVCVVGVRDARY 466
             |||...||...| :|...::..|.. |::|.........|:|..:...|.:..|.|:||.|..:
Human   450 -DGWFKTGDTVVF-KDGQYWIRGRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTW 512

  Fly   467 GDAAGALIIKKEGAEIADQKV 487
            |....|::..:||..::.:::
Human   513 GQRVTAVVTLREGHSLSHREL 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4563	NP_611913.1	CaiC	21..531	CDD:223395	123/541 (23%)
		Firefly_Luc_like	49..521	CDD:213279	123/541 (23%)
ACSF3	XP_005256350.1	MCS	55..546	CDD:341264	117/524 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810