DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4563 and SLC27A4

DIOPT Version :9

Sequence 1:	NP_611913.1	Gene:	CG4563 / 37901	FlyBaseID:	FBgn0035006	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_005085.2	Gene:	SLC27A4 / 10999	HGNCID:	10998	Length:	643	Species:	Homo sapiens

Alignment Length:	506	Identity:	112/506 - (22%)
Similarity:	181/506 - (35%)	Gaps:	98/506 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 IVF-NSLRCWPTNVIQITDDDGTVLTNADMLAYATRIALFFKSEGLTQEDRVGI-IANSSTFV-- 96
            |:| :::|..|.....|.:...|..|...:..|::.:|.|.::.||...|...| :.|.:.||
Human    78 ILFASTVRRHPDKTALIFEGTDTHWTFRQLDEYSSSVANFLQARGLASGDVAAIFMENRNEFVGL 142

  Fly    97 ------IPVATAC----FFQATPFHAVNYSREPAIVQG---------LYSVTKPKI-MFIDGPDY 141
                  :.|..|.    ..:....|.:..||..|:|.|         :::...|.: :|..|
Human   143 WLGMAKLGVEAALINTNLRRDALLHCLTTSRARALVFGSEMASAICEVHASLDPSLSLFCSG--- 204

  Fly   142 DRIKEITKEWSPKLITLTGKVEGVTS-IEDLVKPHPAEKIYVPASLATGGDQIAVVLCSSGTAGL 205
                    .|.|      |.|...|. ::.|:|..|.   ::|:....|.......:.:|||.||
Human   205 --------SWEP------GAVPPSTEHLDPLLKDAPK---HLPSCPDKGFTDKLFYIYTSGTTGL 252

  Fly   206 PKAVALSHRHIASTNSLCI------STDVLYTSATIDWMTGFSITV-MNLTCGFTRIISRRTFSA 263
            |||..:.|.......:|..      ..|::|....:....|..:.: ..|..|.| ::.|:.|||
Human   253 PKAAIVVHSRYYRMAALVYYGFRMRPNDIVYDCLPLYHSAGNIVGIGQCLLHGMT-VVIRKKFSA 316

  Fly   264 ETALYLVSKYKVTCLAMAPWQAYELFTSPLATSEQLESLKIAFVIGGWISLALLRRAQELLPKTY 328
            ........||..|.:.........|...|...:|....:::|  :|..:..::............
Human   317 SRFWDDCIKYNCTIVQYIGELCRYLLNQPPREAENQHQVRMA--LGNGLRQSIWTNFSSRFHIPQ 379

  Fly   329 VMFSYGTTETGVVTINIDHSLECSVGRLAPGMRI------------------KIQGEDGQQLGVN 375
            |...||.||......|.|    ..||......||                  .|:|.||..:..
Human   380 VAEFYGATECNCSLGNFD----SQVGACGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPC- 439

  Fly   376 QTGE--------VLIDIGLKWEGYLSNPEDTATTLQDGWINLGDLGY-------FDEDNNLYLVD 425
            |.||        :..|...:::|||:...:.....:|.: ..||..|       .||...||..|
Human   440 QPGEPGQLVGRIIQKDPLRRFDGYLNQGANNKKIAKDVF-KKGDQAYLTGDVLVMDELGYLYFRD 503

  Fly   426 RKKDLLKYKSKHYWPNEIEQIIAELPEVEHVCVVGVR----DARYGDAAGA 472
            |..|..::|.::....|:|..::.|.::..|.|.||.    :.|.|.||.|
Human   504 RTGDTFRWKGENVSTTEVEGTLSRLLDMADVAVYGVEVPGTEGRAGMAAVA 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4563	NP_611913.1	CaiC	21..531	CDD:223395	112/506 (22%)
CG4563	NP_611913.1	Firefly_Luc_like	49..521	CDD:213279	108/492 (22%)
SLC27A4	NP_005085.2	hsFATP4_like	99..608	CDD:213305	107/485 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149155
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840