Protein Alignment CG4563 and SLC27A5

DIOPT Version :10

• Sequence 1: NP_611913.1
• Gene: CG4563 / 37901
• FlyBaseID: FBgn0035006
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_036386.1
• Gene: SLC27A5 / 10998
• HGNCID: 10999
• Length: 690
• Species: Homo sapiens
• Alignment Length: 604
• Identity: 120/604 - (19%)
• Similarity: 221/604 - (36%)
• Gaps: 146/604 - (24%)

  Fly    17 VWSGPPRPTVYDHNTSVGQIVFNSLRCWPTNVIQITDDDGTVLTNADMLAYATRIALFFKSEGLT 81
            ||:||          ..|.:.|..|.                       |.|.:.|...|:|
Human   134 VWTGP----------GAGSVTFGELD-----------------------ARACQAAWALKAE--- 162

  Fly    82 QEDRVGIIANSSTFVIPVATACFFQATPFHA--------------VN-YSREPAIVQGLYSVTKP 131
            ..|...:.|...|.::.:|:    ||.|...              :| :.|...:...:.| :..
Human   163 LGDPASLCAGEPTALLVLAS----QAVPALCMWLGLAKLGCPTAWINPHGRGMPLAHSVLS-SGA 222

  Fly   132 KIMFIDGPDYDRIKEITKEWSPKL---------ITLTGKVEGVTSIE---DLVKPHPAEKIYVPA 184
            :::.:| ||   ::|..:|..|||         ::.|....||.::.   |....||     |||
Human   223 RVLVVD-PD---LRESLEEILPKLQAENIRCFYLSHTSPTPGVGALGAALDAAPSHP-----VPA 278

  Fly   185 SLATG--GDQIAVVLCSSGTAGLPKAVALSHRHIASTNSL-----CISTDVLYTSATIDWMTGFS 242
            .|..|  ....|:.:.:|||.||||...|:|..:...:.:     ..:.||:||...:..:.|..
Human   279 DLRAGITWRSPALFIYTSGTTGLPKPAILTHERVLQMSKMLSLSGATADDVVYTVLPLYHVMGLV 343

  Fly   243 ITVMN-LTCGFTRIISRRTFSAETALYLVSKYKVTCLAMAPWQAYELFTSPLATSEQLESLKIAF 306
            :.::. |..|.|.:::.: ||.........::.||.:.........|...|....::..::::|
Human   344 VGILGCLDLGATCVLAPK-FSTSCFWDDCRQHGVTVILYVGELLRYLCNIPQQPEDRTHTVRLA- 406

  Fly   307 VIGGWISLALLRRAQELLPKTYVMFSYGTTETGVVTINID------HSLECSVGRLAPGMRIKIQ 365
             :|..:...:....|:......:...||:||..:..:|..      ..:.|.:..|:|...::..
Human   407 -MGNGLRADVWETFQQRFGPIRIWEVYGSTEGNMGLVNYVGRCGALGKMSCLLRMLSPFELVQFD 470

  Fly   366 GE------DGQ----QLGVNQTGEVLID-------IGLKWEGYLSNPEDTATTLQDG--WINLGD 411
            .|      |.|    .:|:.:.|.:|..       :|.:....||..:......|.|  :.|.||
Human   471 MEAAEPVRDNQGFCIPVGLGEPGLLLTKVVSQQPFVGYRGPRELSERKLVRNVRQSGDVYYNTGD 535

  Fly   412 LGYFDEDNNLYLVDRKKDLLKYKSKHYWPNEIEQIIAELPEVEHVCVVGV----RDARYGDAAGA 472
            :...|.:..||..||..|..::|.::...:|:|.:::::..::.|.|.||    .:.:.|.||..
Human   536 VLAMDREGFLYFRDRLGDTFRWKGENVSTHEVEGVLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQ 600

  Fly   473 LIIKKEGAEIADQKVIDHV-----------------AQRVVVDYKQL---------NAGVIFVDK 511
            |   ..|.....:|:..||                 |..|...:|.:         |.|::....
Human   601 L---APGQTFDGEKLYQHVRAWLPAYATPHFIRIQDAMEVTSTFKLMKTRLVREGFNVGIVVDPL 662

  Fly   512 FPKNANGKVMRSLAREVFE 530
            |..:...:..|.|..|:::
Human   663 FVLDNRAQSFRPLTAEMYQ 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4563	NP_611913.1	Firefly_Luc_like	49..521	CDD:341237	110/561 (20%)
SLC27A5	NP_036386.1	hsFATP2a_ACSVL_like	138..680	CDD:341261	117/597 (20%)