Protein Alignment CG3483 and Idh3a

DIOPT Version :10

• Sequence 1: NP_611912.1
• Gene: CG3483 / 37900
• FlyBaseID: FBgn0035005
• Length: 391
• Species: Drosophila melanogaster
• Sequence 2: NP_083849.1
• Gene: Idh3a / 67834
• MGIID: 1915084
• Length: 366
• Species: Mus musculus
• Alignment Length: 352
• Identity: 136/352 - (38%)
• Similarity: 205/352 - (58%)
• Gaps: 23/352 - (6%)

  Fly    47 KQKSKGASGKAKSAGSTDSAKKTTKVTLINGEGVGRELMDAVQEVICAVKAPIEWDVHDEFKAKD 111
            ||.::|.:|..::            ||||.|:|:|.|:..:|.::..|.||||:|:..:....:.
Mouse    21 KQVTRGFAGGVQT------------VTLIPGDGIGPEISASVMKIFDAAKAPIQWEERNVTAIQG 73

  Fly   112 SDD---VSPEVLKSLRANKVGIKG----PVDSRH--WQRQIRKQFAQFAYVSLCSHIEGLDSPYG 167
            ...   :.||..:|:..||:|:||    |:.:.|  ....:||.|..:|.|..|..|||..:||.
Mouse    74 PGGKWMIPPEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYT 138

  Fly   168 DFDVVIIRDQMEGDYSGIEHLVVPGVMQTIKVSTTAGAARIAEFVFNYAVKNKRKRITVAHKANI 232
            |.::|.||:..||:||||||::|.||:|:||:.|...:.|||||.|.||..|.|..:|..|||||
Mouse   139 DVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEEASKRIAEFAFEYARNNHRSNVTAVHKANI 203

  Fly   233 MRMTDGNFLEAMRAEADKHVDDVLFEERYLDTCILKILLKPHKCDVMVSSSMYGDVLRVIAGGMM 297
            |||:||.||:..| |..::..|:.|.|.||||..|.::..|.:.||:|..::|||:|..:..|::
Mouse   204 MRMSDGLFLQKCR-EVAENCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLI 267

  Fly   298 GVPGICPGYSVSSLG-TVFDCRMKACHALAGKDLANPTGPLLSAALMLRHVKMDKQADQVDCAIR 361
            |..|:.|..::.:.| .:|:........:||||:||||..||||.:||||:.:...|.:::.|..
Mouse   268 GGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAAKIEAACF 332

  Fly   362 KVYKDTDIRTPDVGGKAKCSEFVKAVC 388
            ...||....|.|:||.||||:|.:.:|
Mouse   333 ATIKDGKSLTKDLGGNAKCSDFTEEIC 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3483	NP_611912.1	Iso_dh	71..389	CDD:444908	132/328 (40%)
Idh3a	NP_083849.1	mito_nad_idh	29..362	CDD:272942	133/344 (39%)