Protein Alignment CG3483 and IDH3G

DIOPT Version :10

• Sequence 1: NP_611912.1
• Gene: CG3483 / 37900
• FlyBaseID: FBgn0035005
• Length: 391
• Species: Drosophila melanogaster
• Sequence 2: NP_004126.1
• Gene: IDH3G / 3421
• HGNCID: 5386
• Length: 393
• Species: Homo sapiens
• Alignment Length: 326
• Identity: 104/326 - (31%)
• Similarity: 190/326 - (58%)
• Gaps: 13/326 - (3%)

  Fly    72 VTLINGEGVGRELMDAVQEVICAVKAPIEW-DVHDEFKAKDSDDVSPEVLKSLRANKVGIKGPVD 135
            ||:|.|:|:|.|||..|:.|......|::: :||....| |.:|:...:: ::|.|:|.:||.::
Human    57 VTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNA-DEEDIRNAIM-AIRRNRVALKGNIE 119

  Fly   136 SRH--------WQRQIRKQFAQFAYVSLCSHIEGLDSPYGDFDVVIIRDQMEGDYSGIEHLVVPG 192
            :.|        ....:|.....:|.|..|..:.|:.:.:.|.|::|:|:..||:||.:||..|.|
Human   120 TNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAG 184

  Fly   193 VMQTIKVSTTAGAARIAEFVFNYAVKNKRKRITVAHKANIMRMTDGNFLEAMRAEADKHVDDVLF 257
            |::::|:.|.|.:.||||:.|..|.::.||::|..||||||::.||.||:..|..|.:: ..:.|
Human   185 VVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARY-PQITF 248

  Fly   258 EERYLDTCILKILLKPHKCDVMVSSSMYGDVLRVIAGGMMGVPGICPGYSVSSLGTVFDCRMK-A 321
            |...:|...::::.:|.:.||||..::||:::..:..|::|.||:..|.:...:..||:...: .
Human   249 ENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNT 313

  Fly   322 CHALAGKDLANPTGPLLSAALMLRHVKMDKQADQVDCAIRKVYKDTDIRTPDVGGKAKCSEFVKA 386
            ..::|.|::||||..||::.:||.|:|:...|..:..|:.....:.::.|||:||:...||.::.
Human   314 GKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQD 378

  Fly   387 V 387
            |
Human   379 V 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3483	NP_611912.1	Iso_dh	71..389	CDD:444908	104/326 (32%)
IDH3G	NP_004126.1	mito_nad_idh	52..383	CDD:272942	104/326 (32%)